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TranscriptomicsRNA-seq in wild-type and glass mutant eye-antennal discs in Drosophila melanogaster
The aim of this data set is to perform a differential expression analysis between wild type eye-antennal imaginal disc and discs that are homozygous glass mutant gl[60j]. This data set is used to validate Glass target gene predictions identified by i-cisTarget on a set of conserved eye-specific gene...
ORGANISM(S): Drosophila melanogaster 
2012-09-21 | E-GEOD-39781 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of primary hippocampal neurons isolated from mouse E17 embryos and undergoing differentiation in the culture for 7h, 18h, 33h, 72h, 8 days, 12 days (at which time points the RNA was extracted) vs RNA isolated from a newborn brain
A time-course experiment, in which the gene expression in the primary hippocampal neurons isolated from E17 embryos and undergoing differentiation in the culture for 7h, 18h, 33h, 72h, 8 days, 12 days (at which time points the RNA was extracted) was compared by competitive hybridization with a commo...
ORGANISM(S): Mus musculus 
2003-06-01 | E-MEXP-11 | biostudies-arrayexpress
TranscriptomicsSip1 in cortical interneuron migration
We sequenced mRNA from 6 samples of FACsorted telencephalons from E14.5 Sip1|Nkx2-1 knockout and WT|Nkx2-1 control mouse embryos to find differentially expressed genes in the absence of the transcription factor Sip1. Examination of mRNA levels in 3 control and 3 Sip1|Nkx2-1 knockout samples
ORGANISM(S): Mus musculus 
2012-12-07 | E-GEOD-35616 | biostudies-arrayexpress
GenomicsIdentification of lineage-specific cis-regulatory modules associated with variation in transcription factor binding and chromatin activity using Ornstein-Uhlenbeck models
Whole-chromatin profile (FAIRE-seq) in three Drosophila species (D. melanogaster, D. pseudoobscura and D. virilis) in eye-antennal imaginal discs at the stage of third instar wandering larvae. By the use of Ornstein-Uhlenbeck methods, we assess the evolutionary forces acting on regulatory elements (...
ORGANISM(S): Drosophila pseudoobscura 
2015-06-17 | E-GEOD-59706 | biostudies-arrayexpress
GenomicsDiscovery of Transcription Factors and Regulatory Regions Driving In Vivo Tumor Development by ATAC-seq and FAIRE-seq Open Chromatin Profiling
Genomic enhancers regulate spatio-temporal gene expression by recruiting specific combinations of transcription factors (TFs). When TFs are bound to active regulatory regions, they displace canonical nucleosomes, making these regions biochemically detectable as nucleosome-depleted regions or accessi...
ORGANISM(S): Drosophila melanogaster 
2015-02-13 | E-GEOD-59078 | biostudies-arrayexpress
UnknownDiscovery of the p53 targetome in MCF7 cells from RNA-seq data
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-47042 | biostudies-other
TranscriptomicsDiscovery of the p53 targetome in MCF7 cells from RNA-seq data
RNA-seq and ChIP-seq on MCF-7 breast cancer cell line upon activation of p53 by the non-genotoxic small molecule Nutlin-3a RNA-seq on MCF7 without (NS) or with Nutlin-3a stimulation (S), in duplicate, using illumina HiSeq 2000
ORGANISM(S): Homo sapiens 
2014-05-27 | E-GEOD-47042 | biostudies-arrayexpress
GenomicsDiscovery of the p53 targetome in MCF7 cells from ChIP-Seq data
RNA-seq and ChIP-seq on MCF-7 breast cancer cell line upon activation of p53 by the non-genotoxic small molecule Nutlin-3a ChIP-seq on p53 in MCF7 with Nutlin-3a stimulation (S) in triplicate, and the control (input), in stimulated and non stimulated, using illumina HiSeq 2000
ORGANISM(S): Homo sapiens 
2014-05-27 | E-GEOD-47041 | biostudies-arrayexpress
UnknownGenome-wide association study of N370S homozygous Gaucher disease reveals the candidacy of CLN8 gene as a genetic modifier contributing to extreme phenotypic variation.
Not available
S-EPMC3684025 | biostudies-literature
TranscriptomicsAtonal and Senseless perturbations in Drosophila melanogaster eye-antennal imaginal discs.
The goal of this study is to identify co-expressed genes downstream of Atonal and Senseless. These gene lists are used as candidate target genes (technically: as foreground sets) in computational predictions of cis-regulatory elements using the cisTargetX method (http://med.kuleuven.be/cme-mg/lng/ci...
ORGANISM(S): Drosophila melanogaster 
2010-07-29 | E-GEOD-16713 | biostudies-arrayexpress
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