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ModelsAuer2010 - Correlation between lag time and aggregation rate in protein aggregation
Auer2010 - Correlation between lag time and aggregation rate in protein aggregation This model is described in the article: Insight into the correlation between lag time and aggregation rate in the kinetics of protein aggregation. Auer S, Kashchiev D. Proteins 2010 Aug; 78(1...
2024-09-02 | BIOMD0000000555 | BioModels
ProteomicsA proteome scale study reveals how plastic surfaces and agitation promote protein aggregation
Protein aggregation in biotherapeutics can reduce their activity and effectiveness. It may also promote immune reactions responsible for severe adverse effects. The impact of plastic materials on protein destabilization is not totally understood. Here, we propose to deconvolve the effects of materia...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-03-11 | PXD038266 | Pride
A proteome scale study reveals how plastic surfaces and agitation promote protein aggregation 
TranscriptomicsTranscription profiling by array of human peripheral blood mononuclear cells from patients with peripheral arterial disease
Peripheral arterial disease (PAD) is a relatively common manifestation of systemic atherosclerosis that leads to progressive narrowing of the lumen of leg arteries. Circulating monocytes are in contact with the arterial wall and can serve as reporters of vascular pathology in the setting of PAD. We ...
ORGANISM(S): Homo sapiens 
2012-03-22 | E-GEOD-27034 | biostudies-arrayexpress
TranscriptomicsCardiac Gene Expression Profiling in CryAB R120G Transgenic Mice
Protein aggregation cardiomyopathy is a life-threatening manifestation of a multisystem disorder caused by the exchange mutation in the gene encoding the human small HSP ?B-crystallin (hR120GCryAB). Genetic studies in mice have established cardiac hR120GCryAB expression causes increased activity of...
ORGANISM(S): Mus musculus 
2008-12-12 | E-GEOD-9924 | biostudies-arrayexpress
UnknownDetermination of the erythrocyte sedimentation rate using the hematocrit-corrected aggregation index and mean corpuscular volume.
Not available
S-EPMC10156103 | biostudies-literature
GenomicsCadherin adhesion complexes direct cell aggregation in the epithelial transition of Wnt-induced nephron progenitor cells
Cadherin adhesion complexes direct cell aggregation in the epithelial transition of Wnt-induced nephron progenitor cells
PRJNA973005 | ENA
UnknownMeasuring aggregation in parasite populations.
Not available
S-EPMC7211486 | biostudies-literature
MetabolomicsAge-related differences in the gut microbiota and plasma metabolome in dogs: a prospective cross-sectional study under standardized dietary conditions
Background: Aging is associated with progressive metabolic and physiological changes that influence health span in humans and may similarly impact dogs. This study aimed to characterize in the gut microbiota and their associations with host metabolism. Client-owned young adult (2-5 years, > 20 kg, n...
2026-06-26 | MTBLS14861 | MetaboLights
GenomicsResetting proteostasis with calumenin prevents the aggregation of misfolded vimentin during organ fibrosis
Resetting proteostasis with calumenin prevents the aggregation of misfolded vimentin during organ fibrosis
PRJNA1093413 | ENA
ProteomicsEnergy metabolism in skeletal muscle cells from donors with different body mass index
Obesity and physical inactivity have a profound impact on skeletal muscle metabolism. In the present work, we have investigated differences in protein expression and energy metabolism in primary human skeletal muscle cells established from lean donors (BMI<25 kg/m2) and individuals with obesity (BMI...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037909 | Pride
Metabolism Obesity Skeletal muscle cells Mitochondria Eicosapentaenoic acid 
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