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TranscriptomicsExpression data of human trophectoderm cells
The implantation process begins with attachment of the trophectoderm (TE) of the blastocyst to the maternal endometrial epithelium. Herein we have investigated the transcriptome of mural TE cells from 13 human blastocysts and compared these with those of human embryonic stem cell (hESC)-derived-TE (...
ORGANISM(S): Homo sapiens 
2011-09-08 | E-GEOD-30650 | biostudies-arrayexpress
TranscriptomicsPerivascular Human Endometrial Mesenchymal Stem Cells Express Pathways Relevant to Self-Renewal, Lineage Specification, and Functional Phenotype
A population of endometrial cells displaying key properties of mesenchymal stem cells (eMSC) has been identified in human endometrium. eMSC co-express CD146 and PDGFRB surface markers, have a perivascular location, and likely represent the reservoir of progenitors giving rise to the endometrial str...
ORGANISM(S): Homo sapiens 
2011-11-14 | E-GEOD-31152 | biostudies-arrayexpress
TranscriptomicsBone marrow-derived MSC as endometrial stromal progenitor cells
In the current study, we hypothesized that if bone-marrow derived MSC contribute to endometrial regeneration and are progenitors to hESF, their treatment with agents known to regulate hESF differentiation could promote their differentiation down the stromal fibroblast lineage. To this end, we treate...
ORGANISM(S): Homo sapiens 
2010-04-14 | E-GEOD-20631 | biostudies-arrayexpress
TranscriptomicsGlobal transcriptome abnormalities of the eutopic endometrium from women with adenomyosis
Abstract: Objective: Adenomyosis is a clinical disorder defined by the presence of endometrial glands and stroma within the myometrium, the pathogenesis of which is poorly understood. We postulate that dysregulation of genes and pathways in eutopic endometrium may predispose to ectopic implantat...
ORGANISM(S): Homo sapiens 
2016-03-03 | E-GEOD-78851 | biostudies-arrayexpress
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