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MetabolomicsCollected mass spectrometry data on monoterpene indole alkaloids from natural product chemistry research
MIADB: a cumulative collection of 172 tandem mass spectrometry (MS/MS) of a vast array of monoterpene indole alkaloids. Samples were analyzed using an Agilent LC-MS system composed of an Agilent 1260 Infinity HPLC coupled to an Agilent 6530 ESI-Q-TOF-MS operating in positive mode. A Sunfire analytic...
2018-12-03 | MTBLS142 | MetaboLights
MetabolomicsCommon mycelial network modulates neighbour-primed plant defences against foliar pathogens by co-opting distinct inter-plant metabolic and biotic stress responses
This study contains raw and processed mass spectrometry-based metabolomics data from Medicago truncatula plants used to investigate inter-plant signalling through arbuscular mycorrhizal fungal common mycelial networks. The experiment examined metabolomic responses in receiver plants following stress...
2026-06-30 | MTBLS14821 | MetaboLights
ProteomicsPlasma from Rainbow trout housed for 7 days in normoxic and hypoxic water
Hypoxic water had 5 mg/L of Dissolved Oxygen (DO) and normoxic water had 11.5 mg/L DO. 40 immature rainbow trout (about 100 g) were housed for 7 days under these conditions (20 fish in each treatment). Then fish were anesthetized with 100 mg/L MS-222, and blood was sampled using caudal puncture with...
ORGANISM(S): Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) 
2021-06-18 | PXD026589 | Pride
Agilent 6530 qtof Plasma Rainbow trout Shotgun Lc-ms 
MetabolomicsGlobal Metabolomic Profiling of Mice Brains following Experimental Infection with the Cyst-Forming Toxoplasma gondii
The interplay between the Apicomplexan parasite Toxoplasma gondii and its host has been largely studied. However, molecular changes at the metabolic level in the host central nervous system and pathogenesis-associated metabolites during brain infection are largely unexplored. We used a global metabo...
2017-01-27 | MTBLS217 | MetaboLights
MetabolomicsMetabolomic Profiling of Mice Serum during Toxoplasmosis Progression Using Liquid Chromatography-Mass Spectrometry
Better understanding of the molecular changes associated with disease is essential for identifying new routes to improved therapeutics and diagnostic tests. The aim of this study was to investigate the dynamic changes in the metabolic profile of mouse sera during T. gondii infection. We carried out ...
2017-01-25 | MTBLS216 | MetaboLights
UnknownHigh-Resolution Mass Spectrometry for In Vivo Proteome Dynamics using Heavy Water Metabolic Labeling.
Not available
S-EPMC7672638 | biostudies-literature
MetabolomicsMetabolic characterization of the natural progression of chronic hepatitis B (Lipid assays)
Background: Worldwide, over 350 million people are chronically infected with the hepatitis B virus (HBV) and are at increased risk of developing progressive liver diseases. The confinement of HBV replication to the liver, which also acts as the central hub for metabolic and nutritional regulation, e...
2016-06-06 | MTBLS279 | MetaboLights
UnknownQuantitation of 4,4'-methylene diphenyl diisocyanate human serum albumin adducts.
Not available
S-EPMC4748379 | biostudies-literature
ProteomicsDefining, Comparing, and Improving iTRAQ Quantification in Mass Spectrometry Proteomics Data
The purpose of this study was to generate a basis for the decision of what protein quantities are reliable and find a way for accurate and precise protein quantification. To investigate this we have used thousands of peptide measurements to estimate variance and bias for quantification by iTRAQ (iso...
ORGANISM(S): Homo sapiens (Human) 
2013-08-16 | PXD000418 | Pride
Ipg-ief Itraq Lc-ms/ms 
ProteomicsNovel insight into the composition of human single-stranded DNA-binding protein 1 (hSSB1)-containing protein complexes
Single-stranded DNA-binding proteins are essential cellular components required for the protection, metabolism and processing of single-stranded DNA. Human single-stranded DNA-binding protein 1 (hSSB1) is one such protein, with described roles in genome stability maintenance and transcriptional regu...
ORGANISM(S): Homo sapiens (Human) 
2016-12-22 | PXD004686 | Pride
Chromatin remodelling Mrna metabolism Nabp2 Hssb1 Ints3 
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