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Matrix metalloproteinases (MMPs) collectively degrade all extracellular matrix (ECM) proteins. MMP-9 has the strongest link to development of cardiac dysfunction. Aging is associated with increased MMP-9 expression in the left ventricle (LV) and reduced cardiac function. We investigated the effect o...
ORGANISM(S): Mus musculus (Mouse) 
2018-07-05 | PXD002488 | Pride
A systematic investigation of aging patterns across virtually all major tissues in non-human primates, our evolutionarily closest relatives, can provide valuable insights into tissue aging in humans, which is still elusive largely due to the difficulty in sampling. Here, we generated and analyzed mu...
ORGANISM(S): Macaca mulatta (Rhesus macaque) 
2025-11-03 | PXD066108 | Pride
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