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Mutations in the mitochondrial acylglycerol kinase AGK cause Sengers syndrome characterized by cataracts, hypertrophic cardiomyopathy and skeletal myopathy. AGK generates phosphatidic acid and lyso-phosphatidic acid, bioactive phospholipids involved in lipid signaling and the regulation of tumor pro...
ORGANISM(S): Homo sapiens (Human) 
2017-08-14 | PXD006024 | Pride
Mutations in acylglycerol kinase (AGK) leads to Sengers syndrome, a rare disease characterized by skeletal myopathy, hypertrophic cardiomyopathy, and cataracts. AGK, in vitro, produces lysophosphatidic acid and phosphatidic acid via phosphorylation of monoacylglycerol and diacylglycerol, accordingly...
ORGANISM(S): Homo sapiens (Human) 
2020-06-18 | PXD019826 | Pride
Mutations in the mitochondrial acylglycerol kinase AGK cause Sengers syndrome characterized by cataracts, hypertrophic cardiomyopathy and skeletal myopathy. AGK generates phosphatidic acid and lyso-phosphatidic acid, bioactive phospholipids involved in lipid signaling and the regulation of tumor pro...
ORGANISM(S): Homo sapiens (Human) 
2017-08-14 | PXD006023 | Pride
Genomics
Agk 4w 8w oocyte
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