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TranscriptomicsTranscriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq]
Long non-coding RNAs (lncRNAs) have emerged as critical regulators of gene expression and chromatin modifications, with important functions in development and disease. Here we sought to identify and functionally characterize lncRNAs critical for vascular vertebrate development with significant conse...
ORGANISM(S): Homo sapiens 
2015-05-15 | E-GEOD-54968 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [Affymetrix]
Long non-coding RNAs (lncRNAs) have emerged as critical regulators of gene expression and chromatin modifications, with important functions in development and disease. Here we sought to identify and functionally characterize lncRNAs critical for vascular vertebrate development with significant conse...
ORGANISM(S): Homo sapiens 
2015-05-15 | E-GEOD-54964 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [Illumina]
Long non-coding RNAs (lncRNAs) have emerged as critical regulators of gene expression and chromatin modifications, with important functions in development and disease. Here we sought to identify and functionally characterize lncRNAs critical for vascular vertebrate development with significant conse...
ORGANISM(S): Homo sapiens 
2015-05-15 | E-GEOD-54966 | biostudies-arrayexpress
TranscriptomicsIn vivo activation of a conserved microRNA program induces robust mammalian heart regeneration (array)
Heart failure is a leading cause of mortality and morbidity in the developed world, partly because mammals lack the ability to regenerate heart tissue. Whether this is due to evolutionary loss of regenerative mechanisms present in other organisms or to an inability to activate such mechanisms is cur...
ORGANISM(S): Danio rerio 
2014-11-20 | E-GEOD-62386 | biostudies-arrayexpress
TranscriptomicsIn vivo activation of a conserved microRNA program induces robust mammalian heart regeneration (RNA-Seq)
Heart failure is a leading cause of mortality and morbidity in the developed world, partly because mammals lack the ability to regenerate heart tissue. Whether this is due to evolutionary loss of regenerative mechanisms present in other organisms or to an inability to activate such mechanisms is cur...
ORGANISM(S): Rattus norvegicus 
2014-11-20 | E-GEOD-62387 | biostudies-arrayexpress
TranscriptomicsConversion of human fibroblasts into vascular cells (gene expression)
We report a novel technique to reprogram human fibroblasts into endothelial and smooth muscle cells using partial iPSC reprogramming and chemically defined media. Using appropriate media conditions for differentiation of human pluripotent cells to CD34+ vascular progenitor cells, we show that tempor...
ORGANISM(S): Homo sapiens 
2012-09-18 | E-GEOD-40793 | biostudies-arrayexpress
TranscriptomicsConversion of human fibroblasts into vascular cells (methylation)
We report a novel technique to reprogram human fibroblasts into endothelial and smooth muscle cells using partial iPSC reprogramming and chemically defined media. Using appropriate media conditions for differentiation of human pluripotent cells to CD34+ vascular progenitor cells, we show that tempor...
ORGANISM(S): Homo sapiens 
2012-09-18 | E-GEOD-40909 | biostudies-arrayexpress
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