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UnknownAHCTF1 Functions as an Oncogenic Factor and Promotes Tumor Progression in Hepatocellular Carcinoma.
Not available
S-EPMC12627117 | biostudies-literature
Unknownahctf1 and kras mutations combine to amplify oncogenic stress and restrict liver overgrowth in a zebrafish model of hepatocellular carcinoma.
Not available
S-EPMC9897728 | biostudies-literature
UnknownCanonical WNT signaling-dependent gating of MYC requires a noncanonical CTCF function at a distal binding site.
Not available
S-EPMC8752836 | biostudies-literature
UnknownStructural and biochemical analyses of the nuclear pore complex component ELYS identify residues responsible for nucleosome binding.
Not available
S-EPMC6499780 | biostudies-literature
OtherThe WNT-dependent gating of MYC requires non-canonical functions of a distal CTCF binding site
Abnormal WNT signaling increases MYC expression in colon cancer cells in part via oncogenic super-enhancer (OSE)-mediated gating of MYC to the nuclear pore. This process enables MYC transcripts to escape the higher degradation rate in the nucleus compared to the cytoplasm. By targeted mutation, we s...
ORGANISM(S): Homo sapiens 
2021-11-08 | GSE182626 | GEO
GenomicsThe WNT-dependent gating of MYC requires non-canonical functions of a distal CTCF binding site
Abnormal WNT signaling increases MYC expression in colon cancer cells in part via oncogenic super-enhancer-(OSE)-mediated gating of the active MYC to the nuclear pore in a poorly understood process. We show here that that the principal tenet of the WNT-regulated MYC gating, facilitated nuclear expor...
ORGANISM(S): Homo sapiens 
2022-08-31 | GSE182556 | GEO
GenomicsCanonical WNT signaling-dependent gating of MYC requires a non-canonical CTCF function at a distal binding site
Abnormal WNT signaling increases MYC expression in colon cancer cells in part via oncogenic super-enhancer-(OSE)-mediated gating of the active MYC to the nuclear pore in a poorly understood process. We show here that that the principal tenet of the WNT-regulated MYC gating, facilitated nuclear expor...
ORGANISM(S): Homo sapiens 
2021-11-06 | GSE184106 | GEO
TranscriptomicsThe WNT-dependent gating of MYC requires non-canonical functions of a distal CTCF binding site (RNA-Seq II)
Abnormal WNT signaling increases MYC expression in colon cancer cells in part via oncogenic super-enhancer-(OSE)-mediated gating of the active MYC to the nuclear pore in a poorly understood process. We show here that that the principal tenet of the WNT-regulated MYC gating, facilitated nuclear expor...
ORGANISM(S): Homo sapiens 
2021-11-06 | GSE184103 | GEO
UnknownThe zebrafish flotte lotte mutant reveals that the local retinal environment promotes the differentiation of proliferating precursors emerging from their stem cell niche.
Not available
S-EPMC2882130 | biostudies-literature
UnknownThe roles of the cell division cycle-associated gene family in hepatocellular carcinoma.
Not available
S-EPMC8107601 | biostudies-literature
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