The AlaRS mutant of Methylomonas DH-1 showed different lactate tolerance compared to the wild type. Proteomic analysis was conducted to find out what protein changes are related to this reason in the AlaRS mutant strain.
Aminoacyl-tRNA synthetases (AARS) have been increasingly implicated in cancer, although the underlying mechanisms remain unclear. Our analysis reveals that alanyl-tRNA synthetase (AlaRS) is upregulated in head and neck squamous cell carcinoma (HNSCC) tumor cells, with higher expression correlating w...
Aminoacyl-tRNA synthetases (aaRSs) are essential enzymes that provide the ribosome with aminoacyl-tRNA substrates for protein synthesis. Mutations in aaRSs lead to various neurological disorders in humans. Many aaRSs utilize editing to prevent error propagation during translation. Editing defects in...
