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TranscriptomicsAffymetrix Mouse liver gene expression profiling of Cross B6/J x A/J
Summary Mapping the genetic architecture of RNA transcript abundances has potential for revealing molecular mechanisms underlying complex traits like disease. Gene expression microarrays allow monitoring genetic control on a whole transcriptome level, but validity and reproducibility of microarray d...
ORGANISM(S): Mus musculus 
2011-02-02 | E-GEOD-20902 | biostudies-arrayexpress
UnknownHypoxia induced VEGF secretion promotes resistance to bispecific T-cell engagers.
Not available
S-EPMC12715234 | biostudies-literature
ProteomicsLinking soil microbial community traits to the soil storage potential of dissolved organic carbon from surface plant litter
Using Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS) on microcosm samples from early phase plant litter degradation, we found that proteins and condensed hydrocarbons are the compounds with the strongest correlation to dissolved organic carbon (DOC) concentration. Proteins co...
ORGANISM(S): Environmental Samples <bacteria> (ncbitaxon:48479) 
MSV000088109 | MassIVE
TranscriptomicsEffect of lactation on transcriptomic expression in bovine adipose tissue
The objective was to study the transcriptomic changes in adipose tissue in the early stages of lactation, specifically in Bos Taurus, Holstein dairy cattle as a function of milk production and genetic merit. Chip quality backgrounds averaged below 50 units, and 3'/5' bias on control genes < 2.0. Cor...
ORGANISM(S): Bos taurus 
2010-05-27 | E-GEOD-21535 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Burkitts lymphoma cells (L3055) treated with low and high concentrations of CD154
Activated B cells reacting to small amounts of CD40 ligand (CD154) maintain homeostasis by suppressing default apoptosis. Additional outcomes, particularly differentiation, demand higher CD40 occupancy. Here we compared changes in the transcriptome of pleiotropically competent, early-passage L3055 B...
ORGANISM(S): Homo sapiens 
2007-05-31 | E-MEXP-1113 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human native skin, cultured skin substitute, constituent keratinocytes and fibroblasts to identify gene signatures that are highly characteristic of different tissue types
Cultured skin substitutes, prepared using keratinocytes, fibroblasts and biopolymers, can facilitate closure of massive burn wounds by increasing the availability of autologous tissue for grafting. However, because they contain only two cell types, skin substitutes cannot replace all of the functio...
ORGANISM(S): Homo sapiens 
2007-09-06 | E-GEOD-3204 | biostudies-arrayexpress
UnknownSerum circulating proteins from pediatric patients with dilated cardiomyopathy cause pathologic remodeling and cardiomyocyte stiffness.
Not available
S-EPMC8525651 | biostudies-literature
TranscriptomicsMicroarray skeletal muscle PPARbeta overexpressing mice
This experiment was conducted to identify target genes of the peroxisome proliferator-activated receptor beta (PPARb) in skeletal muscle of transgenic mice that overexpressed PPARb. The following abstract from the submitted manuscript describes the major findings of this work. The Nuclear Receptor ...
ORGANISM(S): Mus musculus 
2011-12-12 | E-GEOD-29055 | biostudies-arrayexpress
TranscriptomicsAnalysis of the Pseudomonas aeruginosa regulon controlled by the sensor kinase KinB and sigma factor RpoN
Alginate overproduction by P. aeruginosa, also known as mucoidy is associated with chronic endobronchial infections in cystic fibrosis (CF). Alginate biosynthesis in this bacterium is initiated by the extracytoplasmic function sigma factor (σ22, AlgU/T). In the wild type (wt) nonmucoid strains, su...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2012-03-01 | E-GEOD-35248 | biostudies-arrayexpress
UnknownAssociations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases.
Not available
S-EPMC4586077 | biostudies-literature
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