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TranscriptomicsTranscriptome signature in early biopsies of stably functioning kidney allografts identify patients at risk for chronic injury
Chronic injury in kidney transplants remains a major cause of graft loss. The aim of this study was to identify a predictive gene set capable of classifying renal grafts at risk for progressive injury due to fibrosis.The Genomics of Chronic Allograft Rejection (GoCAR) study is a prospective, multice...
ORGANISM(S): Homo sapiens 
2016-07-20 | E-GEOD-57387 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human blood from kidney transplant patients to identify biomarkers for early and late stage chronic allograft nephropathy by genomic profiling
Despite significant improvements in life expectancy of kidney transplant patients due to advances in surgery and immunosuppression, Chronic Allograft Nephropathy (CAN) remains a daunting problem. A complex network of cellular mechanisms in both graft and peripheral immune compartments complicates th...
ORGANISM(S): Homo sapiens 
2009-07-19 | E-GEOD-12187 | biostudies-arrayexpress
TranscriptomicsMolecular heterogeneity in acute renal allograft rejection
The data set contains 67 array (lymphochip cDNA array), published in N Engl J Med 2003 Jul 10;349(2):125-38. PMID: 12853585. TITLE: Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling. BACKGROUND: The causes and clinical course of acute rejection vary, a...
ORGANISM(S): Homo sapiens 
2003-07-01 | E-GEOD-343 | biostudies-arrayexpress
TranscriptomicsThe Role of Macrophages in the Development of Human Renal Allograft Fibrosis in the First Year after Transplantation
The aim of this study was to investigate the role of infiltrating macrophages in renal allograft fibrosis. Forty-six protocol renal allograft biopsies obtained one-year after transplantation were stained with Sirius Red to quantify fibrosis and double stained with CD68 and CD206 to identify the prop...
ORGANISM(S): Homo sapiens 
2015-01-28 | E-GEOD-65326 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analyses of renal allograft biopsies reveal conserved rejection signatures and molecular pathways
Transcriptomic analyses of renal allograft biopsies reveal conserved rejection signatures and molecular pathways. GEO SuperSeries. This dataset is part of the TransQST collection.
ORGANISM(S): Homo sapiens 
2009-02-24 | E-GEOD-9493 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human renal allograft biopsies reveal conserved rejection signatures and molecular pathways I
Specific early diagnosis of renal allograft rejection is gaining importance in the current trend to minimize and individualize immunosuppression. Gene expression analyses could contribute significantly by defining “molecular Banff” signatures. Several previous studies have applied transcriptomic...
ORGANISM(S): Homo sapiens 
2009-02-28 | E-GEOD-9489 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse autograft and allograft samples from femur
Comparison of autograft and allograft samples from C57Bl/6 femur
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-2249 | biostudies-arrayexpress
GenomicsPretransplant transcriptomic signature in peripheral blood predicts acute rejection and renal allograft loss
Pretransplant transcriptomic signature in peripheral blood predicts acute rejection and renal allograft loss
PRJNA449520 | ENA
TranscriptomicsAnalyses of heterogeneous renal allograft biopsies reveal conserved rejection signatures and molecular pathways I, partB
Specific early diagnosis of renal allograft rejection is gaining importance in the current trend to minimize and individualize immunosuppression. Gene expression analyses could contribute significantly by defining M-bM-^@M-^\molecular BanffM-bM-^@M-^] signatures. Several previous studies have applie...
ORGANISM(S): Homo sapiens 
2009-08-27 | E-GEOD-17861 | biostudies-arrayexpress
UnknownA ferroptosis-related gene signature for graft loss prediction following renal allograft.
Not available
S-EPMC8806795 | biostudies-literature
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