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ProteomicsProteome Analyses of Human NK Cells after alloSCT Challenged byAspergillus fumigatus
We collected longitudinally human NK cells from patients after alloSCT (at days +90, +120, +180), to identify any potential functional NK cell defects on a protein level. We have focused our analysis on whole proteome patterns by analyzing patient NK cells stimulated with A. fumigatus or left unstim...
ORGANISM(S): Neosartorya fumigata (Aspergillus fumigatus) Homo sapiens (Human) 
2026-04-30 | PXD068702 | Pride
Aspergillus fumigatus Nk cells Allosct Lc-ms/ms 
UnknownAdult Patients with Philadelphia-Positive B-Cell Acute Lymphoblastic Leukemia Treated with a Pediatric-Inspired Multiagent Chemotherapy Regimen, in Combination with a TKI, Do Not Require Routine alloSCT.
Not available
S-EPMC12939716 | biostudies-literature
GenomicsHomo sapiens
TCR repertoire of CMV-specific CTLs after alloSCT
PRJDB9600 | ENA
TranscriptomicsscRNAseq of bone marrow (BM) T cells and hematopoietic stem and progenitor cells (HSPCs) of acute myeloid leukemia patients post allogeneic stem cell transplantation (alloSCT).
Gene expression profile at single cell level of bone marrow (BM) T cells and hematopoietic stem and progenitor cells (HSPCs) of acute myeloid leukemia patients post allogeneic stem cell transplantation (alloSCT) of patients in complete remission (CR) and relapse (REL).
ORGANISM(S): Homo sapiens 
2024-01-11 | GSE216187 | GEO
GenomicsscRNAseq of bone marrow (BM) T cells and hematopoietic stem and progenitor cells (HSPCs) of acute myeloid leukemia patients post allogeneic stem cell transplantation (alloSCT).
scRNAseq of bone marrow (BM) T cells and hematopoietic stem and progenitor cells (HSPCs) of acute myeloid leukemia patients post allogeneic stem cell transplantation (alloSCT).
PRJNA892527 | ENA
TranscriptomicsReduced proliferation capacity of native bone marrow MSC after allogenic stem cell transplantation is associated with clinical outcome
Engraftment and differentiation of donor hematopoietic stem cells is decisive for the clinical success of allogeneic stem cell transplantation (alloSCT) and depends on the recipient’s bone marrow (BM) niche. Presumably, a damaged niche contributes to poor graft function post-alloSCT, but the underly...
ORGANISM(S): Homo sapiens 
2023-05-01 | GSE203246 | GEO
TranscriptomicsAddition of IL-6 inhibition to standard GVHD prophylaxis to prevent GVHD after allogeneic stem cell transplantation
BACKGROUND - IL-6 mediates graft-versus-host disease (GVHD) in experimental allogeneic stem cell transplantation (alloSCT) and is an attractive therapeutic target. METHODS - A registered phase I/II study (ACTRN12612000726853) of IL-6 receptor (IL-6R) neutralizing antibody administration on day -1 to...
ORGANISM(S): Homo sapiens 
2014-09-09 | E-GEOD-61201 | biostudies-arrayexpress
TranscriptomicsMolecular profiling reveals human biomarker signatures in patients after allogeneic stem cell transplantation suffering from invasive aspergillosis
Despite available diagnostic tests and recent advances, diagnosis of pulmonary invasive aspergillosis (IPA) remains challenging. By undertaking a longitudinal case-control study, we explored the possibility to identify novel non-invasive human biomarkers candidates for IPA in patients post allogenei...
ORGANISM(S): Homo sapiens 
2022-03-02 | GSE174825 | GEO
TranscriptomicsAddition of IL-6 inhibition to standard GVHD prophylaxis to prevent GVHD after allogeneic stem cell transplantation
BACKGROUND - IL-6 mediates graft-versus-host disease (GVHD) in experimental allogeneic stem cell transplantation (alloSCT) and is an attractive therapeutic target. METHODS - A registered phase I/II study (ACTRN12612000726853) of IL-6 receptor (IL-6R) neutralizing antibody administration on day -1 to...
ORGANISM(S): Homo sapiens 
2014-09-09 | GSE61201 | GEO
UnknownReduced proliferation of bone marrow MSC after allogeneic stem cell transplantation is associated with clinical outcome.
Not available
S-EPMC10279553 | biostudies-literature
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