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Dasatinib has demonstrated efficacy in patients with chronic-phase chronic myeloid leukemia (CML) who had resistance or intolerance to imatinib. However, some patients also develop resistance or intolerance to dasatinib. To identify potential molecular pathways involved in primary resistance to dasa...
ORGANISM(S): Homo sapiens 
Dasatinib has demonstrated efficacy in patients with chronic-phase chronic myeloid leukemia (CML) who had resistance or intolerance to imatinib. However, some patients also develop resistance or intolerance to dasatinib. To identify potential molecular pathways involved in primary resistance to dasa...
ORGANISM(S): Homo sapiens 
Cyanobacterial blooms associated with the benthic mat have been rising. Besides the ongoing concern about toxins production, cyanobacteria are actively involved in marine biofilms, representing several economic and environmental impacts. Proteomic studies on cyanobacterial biofilms could be an effec...
ORGANISM(S): Synechococcales cyanobacterium LEGE 06021 
2022-10-13 | PXD029048 | Pride
Background: Treatment and morbidity control of schistosomiasis relies on a single drug, praziquantel. Therefore, there is a pressing need to explore the effects of PZQ on the parasites at the molecular level and to pursue alternative and/or or synergistic drugs against schistosomiasis. Methodology...
ORGANISM(S): Schistosoma mansoni 
Transcriptional profiling of S. mansoni pairing-experienced males (EM) vs. pairing unexperienced males (UM) Two conditions (EM vs. UM) with three biological samples of EM and in parallel other three biological samples of UM. For each sample (three EM and three UM) were performed four technical rep...
ORGANISM(S): Schistosoma mansoni 
Fungal secondary metabolites constitute a rich source of yet undiscovered bioactive compounds. Their production is often silent under standard laboratory conditions, but the production of some compounds can be triggered simply by altering the cultivation conditions. The usage of an organic salt - io...
2022-07-15 | MTBLS5072 | MetaboLights
Cork quality is a technological trait of large interest for the Mediterranean cork industry. Our manuscript analyses the proteins and phenolics of cork producing cells in order to collect data about the molecular/biochemical pathways determining cork quality. To the best of our knowledge, this infor...
ORGANISM(S): Quercus suber (Cork oak) 
2019-07-09 | PXD014398 | Pride
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