Alr - OmicsDI

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Transcriptomics (412)
Unknown (331)
Genomics (187)
Proteomics (50)
Metabolomics (7)
Other (3)
Models (2)
Genomic (1)

Organisms

Homo sapiens (298)
Mus musculus (98)
Caenorhabditis elegans (37)
Rattus norvegicus (18)
Triticum aestivum (11)
Drosophila melanogaster (11)
Zea mays (8)
Anopheles gambiae (8)
Arabidopsis thaliana (8)
Sus scrofa (7)
Rhizobium leguminosarum (6)
Schizosaccharomyces pombe (6)
Xylella fastidiosa (5)
Saccharomyces cerevisiae (4)
Danio rerio (4)
Macaca mulatta (3)
Gallus gallus (3)
Blastocladiella emersonii (2)
Amphiura filiformis (2)
Oryza sativa (2)
Aedes aegypti (2)
Octopus vulgaris (1)
Plutella xylostella (1)
Teleopsis quinqueguttata (1)
Triticum turgidum subsp. durum (1)
human gut metagenome (1)
Lytechinus pictus (1)
Paracentrotus lividus (1)
Strongylocentrotus purpuratus (1)
Tribolium castaneum (1)

Organisms

Mus musculus (8)
Homo sapiens (6)
Lactococcus cremoris subsp. cremoris MG1363 (3)
Pseudomonas putida KT2440 (1)
Acinetobacter baumannii (1)
root metagenome (1)

Repository

biostudies-arrayexpress (470)
EGA (84)
MassIVE (39)
ENA (29)
geo (19)
pride (9)
MetaboLights (7)
BioModels (2)
PanoramaPublic (2)
dbGaP (1)
EVA (1)
jPOST (1)

Tissue

Cell culture (4)
HTERT-RPE1 cell (2)
Fibroblast (1)
Epithelial cell (1)
B cell (1)
Blood (1)

Disease

Teratozoospermia and infertility (1)
Ductal carcinoma (1)
Coronary artery disease (1)
Wilms tumour (1)
Normal (1)
Breast cancer (1)

Technology Type

Mass Spectrometry (9)
Mass spectrometry assay (4)
Shotgun proteomics (4)
Illumina HiSeq 2000 (3)
Mass spectrometry (3)
Illumina MiSeq (2)
Data-dependent acquisition (2)
Affinity purification coupled with mass spectrometry proteomics (2)
Illumina HiSeq 2500, ILLUMINA (1)
Illumina HiSeq 2500 (1)
Illumina Infinium 1.2M (1)
SWATH MS (1)

Instrument Platform

Orbitrap Fusion Lumos (22)
Illumina HiSeq 2000 (10)
Illumina NovaSeq 6000 (8)
NextSeq 500 (7)
Illumina HiSeq 4000 (6)
Illumina HiSeq 2500 (5)
Illumina NovaSeq X (2)
Ion Chef (2)
Ion Torrent S5 XL (2)
Illumina HiSeq 1500 (2)
NextSeq 550 (2)
Illumina HiSeq 3000 (2)
Applied BiosystemsTM GeneChipTM Whole Transcript (WT) PLUS Reagent Kit User Guide (Thermo Fisher Scientific, Waltham, MA, USA). (1)
Applied BiosystemsTM GeneChipTM Clariom S human arrays (1)
PAXgene Blood RNA Kit (PreAnalytiX, Hombrechtikon, Switzerland). (1)
10x Chromium v3 (1)
GeneChip Scanner 3000 (1)
MagNA Lyser (1)
Affymetrix Gene Titan (1)
Affymetrix GeneChip(R) HT Scanner (1)
Gene Titan (1)
G2505A DNA microarray scanner [Agilent] (1)
DNA Microarray Scanner BA [Agilent Technologies] (1)
Illumina Genome Analyzer II (1)
NextSeq 1000 (1)
FACS Aria-III (1)
Illumina HiSeq X (1)
Ion Torrent Proton (1)
BGISEQ-500 (1)
Ion S5XL (1)

Publication Date

2013 (62)
2014 (55)
2011 (53)
2010 (48)
2012 (46)
2015 (41)
2016 (39)
2008 (35)
2023 (21)
2009 (20)
2020 (19)
2025 (18)
2024 (17)
2022 (16)
2021 (14)
2026 (12)
2018 (7)
2017 (7)
2007 (6)
2006 (4)
2019 (4)
2005 (3)
2004 (1)

UNIPROT ID/AC

O25420 (1)
Q48271 (1)
O25044 (1)
O25333 (1)
O25332 (1)
O25786 (1)
O25071 (1)
O25342 (1)
O26078 (1)
O26085 (1)
O26018 (1)
O25376 (1)
O25488 (1)
Q48262 (1)
O25014 (1)
O26011 (1)
O25838 (1)
O25551 (1)
O25150 (1)
O25011 (1)
O26077 (1)
O25505 (1)
P56003 (1)
O25122 (1)
O25124 (1)
P56117 (1)
P56176 (1)
O25872 (1)
O26103 (1)
O26102 (1)

CHEBI ID

CHEBI:30816 (2)
CHEBI:62959 (1)
CHEBI:62958 (1)
CHEBI:32797 (1)
CHEBI:380 (1)
CHEBI:11036 (1)
CHEBI:16782 (1)
CHEBI:18739 (1)
CHEBI:18738 (1)
CHEBI:62621 (1)
CHEBI:26638 (1)
CHEBI:47569 (1)
CHEBI:9098 (1)
CHEBI:27277 (1)
CHEBI:46315 (1)
CHEBI:27278 (1)
CHEBI:15301 (1)
CHEBI:9933 (1)
CHEBI:16632 (1)
CHEBI:46497 (1)
CHEBI:46502 (1)
CHEBI:36272 (1)
CHEBI:30518 (1)
CHEBI:36271 (1)
CHEBI:26894 (1)
CHEBI:9474 (1)
CHEBI:45729 (1)
CHEBI:27902 (1)
CHEBI:71392 (1)
CHEBI:77932 (1)

Metabolite Name

Tromethamine, 3TMS derivative (1)
Trimethylsilylpropargyl alcohol, 2TMS derivative (1)
Succinic acid, 2,2,3,3,4,4,5,5-octafluoropentyl 2-methylpent-3-yl ester (1)
Serine, 3TMS derivative (1)
Pyroglutamic acid, TMS derivative (1)
Propanoic acid, 3-[(tert-butyldimethylsilyl)oxy]-2-methyl-, tert-butyldimethylsilyl ester (1)
Propanedioic acid, 2TBDMS derivative (1)
Phthalic acid, di(3-methylphenyl) ester (1)
Phosphorylethanolamine, 4TMS derivative (1)
Phosphoric acid, bis[2,3-bis[(trimethylsilyl)oxy]propyl] trimethylsilyl ester (1)
Phosphonic acid, (aminomethyl)-, bis(trimethylsilyl) ester (1)
Phenylethyl Alcohol, TMS derivative (1)
Phenylalanine, 2TMS derivative (1)
Octanoic acid, tributylsilyl ester (1)
N-Acetyl-L-glutamic acid, 2TMS derivative (1)
N-.alpha.-Acetyl-L-Lysine, 3TMS derivative (1)
Myrtenoic acid, trimethylsilyl ester (1)
Monolaurin, 2TMS derivative (1)
Methyltris(trimethylsiloxy)silane (1)
Methylsuccinic acid, 2TMS derivative (1)
Mercaptoacetic acid, 2TMS derivative (1)
Malonic acid, bis(2-trimethylsilylethyl ester (1)
Lysine, 3TMS derivative (1)
L-Valine, TMS derivative (1)
L-Threonine, 3TMS derivative (1)
L-Serine, 2TMS derivative (1)
L-Proline, TMS derivative (1)
L-Proline, n-propargyloxycarbonyl-, propargyl ester (1)
L-Proline, 2TMS derivative (1)
L-Phenylalanine, 2TMS derivative (1)

First Public Date

2026 (5)
2025 (4)
2024 (4)
2022 (3)
2020 (3)
2016 (3)
2019 (2)
2017 (2)
2018 (1)
2015 (1)
2014 (1)

Modelling Approach

Constraint-based model (2)

Lab affiliation

Redox Metabolism, Institute for Biochemistry, University of Cologne (3)
Cambridge Institute for Medical Research, University of Cambridge, UK (2)
Institute of Biochemistry II; University Hospital of Goethe University Frankfurt Building 75 ,Ground floor, Room 0.205 Theodor-Stern-Kai 7 60590 Frankfurt am Main, Germany (1)
James McGill Professor, Montreal Neurological Institute, McGill University (1)
University of Cambridge (1)
Institute of Toxicology and Environmental Hygiene, Technical University of Munich, School of Medicine, Munich, Germany Institute of Molecular Toxicology and Pharmacology, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany (1)

IsPrivate

False (2)

Submitter Keywords

FROG (1)

Classification

bacteria (1)

Study type

Transcription profiling by array (211)
ChIP-seq (60)
RNA-seq of coding RNA (50)
Comparative genomic hybridization by array (43)
RNA-seq of non coding RNA (31)
Unknown experiment type (11)
Other (10)
Genotyping by array (8)
ChIP-chip by tiling array (6)
RNA-seq of coding RNA from single cells (6)
DNA-seq (5)
Transcription profiling by tiling array (4)
Methylation profiling by high throughput sequencing (3)
RNA-seq of total RNA (3)
ChIP-chip by array (2)
Spatial transcriptomics by high-throughput sequencing (2)
Differential (1)
Human - Two-color microarray (1)
Human - Methylation microarray (1)
Human - Single-cell sequencing (1)
Plant - High-throughput sequencing (1)
Cell line - High-throughput sequencing (1)
Transcription profiling by RT-PCR (1)
4C (1)
Hi-C (1)
MicroRNA profiling by array (1)
Methylation profiling by array (1)
CUT&RUN (1)
Genotyping by high throughput sequencing (1)

Release Date

2013 (71)
2014 (69)
2011 (57)
2012 (54)
2010 (52)
2015 (51)
2016 (45)
2022 (43)
2021 (43)
2023 (42)
2008 (40)
2025 (38)
2024 (36)
2020 (34)
2017 (29)
2018 (25)
2009 (21)
2019 (18)
2026 (9)
2007 (8)
2006 (4)
2005 (4)
2003 (3)
2002 (2)
2000 (2)
2004 (1)

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Cycloserin Resistance and Alr mutations

PRJEB19271 | ENA

Definition of the ALR interactome by IP and AP under different lysis conditions

Interactome of overexpressed HA-tagged (2771, 2918) or Strep-tagged (3555, 3592) ALR in HEK293 FLP/IN/T-Rex cells vs control Mock under native (2771, 3592) or denaturing (2883, 3555) lysis conditions. For project 2771, an interactome of HA-tagged SOD2 was generated as additional negative control.

ORGANISM(S): Homo sapiens (Human)

2026-04-16 | PXD064631 | Pride

Identification of Transcription Factor ALR-1::GFP Binding Regions in L2

modENCODE_submission_3156 This submission comes from a modENCODE project of Michael Snyder. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We are identifying the DNA binding sites for 300 transcription factors in C. elegans. Each transcription factor gene is ta...

ORGANISM(S): Caenorhabditis elegans

2011-03-31 | E-GEOD-25787 | biostudies-arrayexpress

ALR Couples IMS Redox and Heme Biosynthesis Beyond the Disulfide Relay

Denaturing pulldown of ALR-HA from HEK293 cells to identify the covalent interaction partners of ALR. One half of the samples were treated with DTT during the Co-IP protocol to verify that the interactions are disulfide related. Accordingly, no Mock-cell lines was used. One half of the samples from ...

ORGANISM(S): Homo sapiens (Human)

2026-04-16 | PXD075266 | Pride

Heme biosynthesis Oxidative protein folding Mitochondria

Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.

Not available

S-EPMC1820476 | biostudies-literature

Inhibiting the Mitochondrial Sulfhydryl Oxidase ALR reduces levels of Mitochondrial COX17 and induces Differentiation of AML Cells

PRJNA418927 | ENA

Augmenter of liver regeneration (alr) promotes liver outgrowth during zebrafish hepatogenesis.

Not available

S-EPMC3266923 | biostudies-literature

root metagenome isolate:ALR