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TranscriptomicsCopy number alterations of 103 hepatocellular carcinomas with hepatitis C virus etiology
To characterize the genetic alterations that instigate hepatitis C virus-induced hepatocellular carcinoma (HCC), we conducted an integrative genomic analysis of 103 HCCs. Most tumors harbored 1q gain, 8q gain or 8p loss, with occasional alterations in 13 additional chromosome arms. In addition to ...
ORGANISM(S): Homo sapiens 
2008-06-21 | E-GEOD-9845 | biostudies-arrayexpress
TranscriptomicsRobust temporal map of human in vitro myelopoiesis using single-cell genomics (ATAC data)
We performed a detailed analysis of the in vitro differentiation of induced pluripotent stem cells to macrophages and dendritic (chromatin accessibility data).
ORGANISM(S): Homo sapiens 
2022-04-28 | E-MTAB-11616 | biostudies-arrayexpress
UnknownMicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a.
Not available
S-EPMC3680790 | biostudies-literature
TranscriptomicsmicroRNA profiling of human hepatocellular carcinoma
microRNA profiling of 89 human hepatocellular carcinoma tissues using bead-based technology. microRNA expression profiling was performed using freshly frozen hepatocellular carcinoma tissues obtained at the time of surgical treatment.
ORGANISM(S): Homo sapiens 
2011-02-17 | E-GEOD-20594 | biostudies-arrayexpress
TranscriptomicsmRNA expression profile modified by microRNA mir-517a (MIR517A) in human hepatocellular carcinoma cell line
mRNA expression profile modified by stable transfection of microRNA mir-517a (MIR517A) in a human hepatocellular carcinoma cell line Huh-7 Keywords: Hepatocellular carcinoma, Expression array, microRNA microRNA mir-517a (MIR517A) was transfected to Huh-7 cells using GFP-expressing lentiviral vector...
ORGANISM(S): Homo sapiens 
2011-02-17 | E-GEOD-20679 | biostudies-arrayexpress
TranscriptomicsFocal gains of VEGFA and molecular classification of hepatocellular carcinoma
The data are derived from anonymized patient samples for which demographic information is not provided This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2008-06-22 | E-GEOD-9829 | biostudies-arrayexpress
TranscriptomicsTonsil Atlas FASTQ files
This repository contains all the FASTQ files for the five data modalities (scRNA-seq, scATAC-seq, Multiome, CITE-seq+scVDJ-seq, and spatial transcriptomics) used in the article \\"An Atlas of Cells in The Human Tonsil,\\" published in Immunity in 2024. Inspired by the TCGA barcodes, we have named ea...
ORGANISM(S): Homo sapiens 
2024-05-02 | E-MTAB-13687 | biostudies-arrayexpress
TranscriptomicsGene-expression profiles of formalin-fixed, paraffin-embedded human hepatocellular carcinoma
Gene-expression profiles of formalin-fixed, paraffin-embedded human hepatocellular carcinoma tissues obtained at the time of surgical resection. Gene-expression profiling was performed using formalin-fixed, paraffin-embedded hepatocellular carcinoma tissues obtained at the time of surgical resection...
ORGANISM(S): Homo sapiens 
2011-02-17 | E-GEOD-19977 | biostudies-arrayexpress
TranscriptomicsMicroRNA-Based Classification of Hepatocellular Carcinoma and Oncogenic Role of miR-517a
Hepatocellular carcinoma (HCC) is a complex and heterogeneous tumor due to activation of multiple cellular pathways and molecular alterations. Herein, we report the first molecular classification of 89 HCC based on the expression of 358 microRNAs and integrative genomic analysis. Three main subclass...
ORGANISM(S): Homo sapiens 
2011-02-17 | E-GEOD-20596 | biostudies-arrayexpress
TranscriptomicsExpression profiling of Notch constitutive activation in the liver of mice
Notch intracellular domain (NICD) is the active form of the Notch receptor. In this mouse model, NICD is inserted in the Rosa26 locus downstream of a loxP-STOP-LoxP (lsl) sequence and therefore NICD expression is dependant on Cre recombinase expression (Mono transgenic control Rosa26-lsl-NICD) . The...
ORGANISM(S): Mus musculus 
2012-12-01 | E-GEOD-33560 | biostudies-arrayexpress
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