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MetabolomicsSystemic impact of the expression of the mitochondrial alternative oxidase on Drosophila development
Not available
ORGANISM(S): Drosophila melanogaster 
ST002069 | MetabolomicsWorkbench
ProteomicsComplexome profiling of heart mitochondria from mouse expressing alternative oxidase
Ciona intestinalis alternative oxidase (AOX) is a mitochondrial respiratory enzyme that acts as an alternative electron sink for ubiquinol (reduced quinone) when the cytochrome bc1 complex (complex III) and/or cytochrome c oxidase (complex IV) are inhibited or impaired (El-Khoury et al., 2014). AOX ...
ORGANISM(S): Mus musculus (Mouse) 
2019-12-13 | PXD014016 | Pride
Alternative oxidase Mitochondria Lc-msms Complexome profiling 
TranscriptomicsArabidopsis plants with altered levels of alternative oxidase
In higher plants, various developmental and environmental conditions enhance expression of the mitochondrial alternative oxidase (AOX). In this work transgenic Arabidopsis thaliana plants were generated that either overexpress AOX or inhibit its synthesis. Gene expression following antimycin A treat...
ORGANISM(S): Arabidopsis thaliana 
2007-06-28 | E-GEOD-4113 | biostudies-arrayexpress
TranscriptomicsResponse to antimycin A in wild type Arabidopsis and in alternative oxidase overexpresser
In higher plants, various developmental and environmental conditions enhance expression of the mitochondrial alternative oxidase (AOX). In this work transgenic Arabidopsis thaliana plants were generated that either overexpress AOX or inhibit its synthesis. Gene expression following antimycin A treat...
ORGANISM(S): Arabidopsis thaliana 
2010-07-01 | E-GEOD-4141 | biostudies-arrayexpress
TranscriptomicsTranscriptomics study on the effect of alternative oxidase expression in Bcs1l mutant (S78G) mice (Mus musculus)
The dataset contains 72 RNA-seq samples obtained from adult (P150) C57BL/6JCrl mice. Samples are from total heart, liver and kidney tissue. Four different genotypes are included in the data: 1) wild type, 2) transgenic Ciona intestinalis AOX in Rosa26 locus (Szibor et al. 2017, DOI: 10.1242/dmm.0278...
ORGANISM(S): Mus musculus 
2018-11-16 | E-MTAB-7416 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis Col-0 vs. AtAOX1a antisense treated plants
Leaf transcriptome comparison of untransformed Col-0 Arabidopsis plants with plants transformed to be anti-sense for AtAOX1a (alternative oxidase). Two “bio-replicates” were sampled, for a total of four microarray chips—Col-0 and anti-sense leaf tissue from a first planting (samples GSM45208 ...
ORGANISM(S): Arabidopsis thaliana 
2008-06-12 | E-GEOD-2406 | biostudies-arrayexpress
ProteomicsCOX6B1 secures a redox-sensitive step in early cytochrome c oxidase assembly
COX6B is one of the eleven nuclear-encoded subunits of the human mitochondrial inner-membrane cytochrome c oxidase (cIV), which is located in the intermembrane space-facing region of cIV. In mammals, there are two COX6B isoforms: the ubiquitous isoform COX6B1, expressed in all cell types and tissues...
ORGANISM(S): Homo sapiens (Human) 
2025-12-15 | PXD061618 | Pride
Mitochondria Alternative oxidase (aox) Cytochrome c oxidase Respiratory chain biogenesis Complexome profiling 
ProteomicsExpression of Ciona intestinalis alternative oxidase (AOX) in a mouse model of cardiac ischemia-reperfusion
The objective of this study was to test how restoration of mitochondrial respiration using AOX affects the development of cardiac ischemia-reperfusion (IR) injuries in C57BL/ 6J mice. AOX transgenic mice have Ciona intestinalis AOX coding sequence knocked into the Rosa26 locus with AOX expression co...
ORGANISM(S): Mus musculus (Mouse) 
2020-01-30 | PXD014061 | Pride
Mitochondrial respiration Mitochondrial electron transport chain (etc) Mitochondria Alternative oxidase (aox) Cardiac ischemia-reperfusion 
TranscriptomicsTranscriptome analysis of the shoots of Arabidopsis wild-type and mutants deficient in either or both activities of nitrate reductase and alternative oxidase
The conversion of nitrate to ammonium, known as nitrate reduction, consumes large amounts of reductants in plants. Previous studies have observed that mitochondrial alternative oxidase (AOX) is upregulated under conditions of limited nitrate reduction, such as low or no nitrate availability, or when...
ORGANISM(S): Arabidopsis thaliana 
2024-04-23 | E-MTAB-14027 | biostudies-arrayexpress
TranscriptomicsResponse to antimycin A in wild type Arabidopsis and in alternative oxidase overexpresser
In higher plants, various developmental and environmental conditions enhance expression of the mitochondrial alternative oxidase (AOX). In this work transgenic Arabidopsis thaliana plants were generated that either overexpress AOX or inhibit its synthesis. Gene expression following antimycin A treat...
ORGANISM(S): Arabidopsis thaliana 
2006-02-02 | GSE4141 | GEO
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