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UnknownModulation of the Adjuvant Potential of Imidazoquinoline-Based TLR7/8 Agonists via Alum Adsorption.
Not available
S-EPMC11472459 | biostudies-literature
ProteomicsMonocyte responses to Al(OH)3 adjuvant
Monocytes, derived from three different donors, were stimulated with the vaccine adjuvant Al(OH)3 for 24 and 48 hours. Proteins were isolated and equal protein amounts were labeledusing TMT(6). We found that Al(OH)3 activates various pathways related to the innate immune response.
ORGANISM(S): Homo sapiens (Human) 
2018-03-27 | PXD008452 | Pride
Alum-based adjuvant Innate immune response Quantitative proteomics 
UnknownAlum as an adjuvant for nanoparticle based vaccines: A case study with a hybrid nanoparticle-based nicotine vaccine.
Not available
S-EPMC6702048 | biostudies-literature
TranscriptomicsscRNA-seq profiling of lymph node activation in non-human primate Rhesus macaques by aluminum hydroxide and saponin adjuvant SMNP
Saponin-based vaccine adjuvants are potent in preclinical animal models and humans, but their mechanisms of action remain poorly understood. Using a stabilized HIV envelope trimer as a model immunogen, we carried out studies in non-human primates (NHPs), comparing the most common clinical adjuvant a...
ORGANISM(S): Macaca mulatta 
2024-07-01 | GSE264685 | GEO
UnknownA Novel Bacterial Protease Inhibitor Adjuvant in RBD-Based COVID-19 Vaccine Formulations Containing Alum Increases Neutralizing Antibodies, Specific Germinal Center B Cells and Confers Protection Against SARS-CoV-2 Infection in Mice.
Not available
S-EPMC8919065 | biostudies-literature
UnknownA yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates.
Not available
S-EPMC9119307 | biostudies-literature
UnknownPreclinical evaluation of immunogenicity, efficacy and safety of a recombinant plant-based SARS-CoV-2 RBD vaccine formulated with 3M-052-Alum adjuvant.
Not available
S-EPMC10027959 | biostudies-literature
UnknownRNA is an Adjuvanticity Mediator for the Lipid-Based Mucosal Adjuvant, Endocine.
Not available
S-EPMC4931589 | biostudies-literature
UnknownEffective inhibition of melanoma tumorigenesis and growth via a new complex vaccine based on NY-ESO-1-alum-polysaccharide-HH2.
Not available
S-EPMC4120012 | biostudies-literature
UnknownDisparate adjuvant properties among three formulations of "alum".
Not available
S-EPMC3541451 | biostudies-literature
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