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ProteomicsSOX11-SMARCA4 Complex Drives Oncogenic Gene Regulation in Mantle Cell Lymphoma
SOX11 pioneer transcription factor is aberrantly expressed, it has an oncogenic role and its overexpression associates with worse prognosis in patients with mantle cell lymphomas (MCL). Using a proximity labeling (BioID2)/Mass Spectrometry-based proteomic strategyies, we identified SMARCA4, the cent...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD051143 | Pride
Smarca4 Cut&run-sequencing. Sry-related hmg-box 11 (sox11) Mantle cell lymphoma Swi/snf chromatin remodeling complex Pioneer transcription factor 
TranscriptomicsSOX11-positive and SOX11-knockdown xenograft derived tumor Gene Expression Profilings
The neural transcription factor SOX11 is overexpressed in aggressive lymphoid neoplasms mainly in mantle cell lymphoma (MCL). We have recently demonstrated SOX11 tumorigenic potential in vivo by showing a significant reduction on tumor growth of SOX11-knockdown MCL cells in xenograft experiments, co...
ORGANISM(S): Homo sapiens 
2014-11-04 | E-GEOD-52892 | biostudies-arrayexpress
TranscriptomicsSOX11 Gene Expression Profiling
The neural transcription factor SOX11 is overexpressed in aggressive lymphoid neoplasms mainly in mantle cell lymphoma (MCL), but its functional role in malignant B-cells is unknown. To identify target genes transcriptionally regulated by SOX11 in malignant lymphoid cells, we have used Gene Expressi...
ORGANISM(S): Homo sapiens 
2013-04-04 | E-GEOD-34763 | biostudies-arrayexpress
TranscriptomicsMicroenvironment-related long non-coding RNAs (LINC00152) in CLL
RNAseq was performed on 3 primary CLL paired samples with LINC00152 silencing vs Scrambled controls either growing in presence of a mix of micorenvironment- related agonist factor mix and Ibrutinib drug, as in a control (DMSO) medium without such factors/drug.
ORGANISM(S): Homo sapiens 
2026-08-15 | E-MTAB-17232 | biostudies-arrayexpress
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