Identification and relative quantification of aminopeptidase-B and other bioconverting enzymes in mouse brain, liver, and plasma tissues as well as in BV2 microglia cells.
Human leukocyte antigen (HLA) - B*51:01 and endoplasmic reticulum aminopeptidase 1 (ERAP1) are two strong predisposing genetic factors to Behçet's disease (BD). Previous studies have focused on two subgroups of HLA-B*51 peptidome containing Proline (Pro) or Alanine (Ala) at position 2 (P2). Little i...