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Fertility preservation research in women today is increasingly taking advantage of bioengineering techniques to develop new biomimetic materials and solutions to safeguard ovarian cell function and microenvironment in vitro and in vivo. However, available data on the human ovary are limited and fund...
ORGANISM(S): Homo sapiens (Human) 
2018-02-27 | PXD008183 | Pride
Currently, the extracellular matrix (ECM) is considered a pivotal complex meshwork of macromolecules playing a plethora of biomolecular functions in health and disease beyond its commonly known mechanical role. Only by unravelling its composition, we can leverage related tissue engineering and pharm...
ORGANISM(S): Homo sapiens (Human) 
2020-12-03 | PXD020823 | Pride
Our modern era is witnessing an increasing infertility rate worldwide. Although some of the causes can be attributed to our modern lifestyle (eg. persistent organic polluants, late pregnancy), our knowledge of the human ovarian tissue has remained limited and insufficient to reverse the infertility ...
ORGANISM(S): Homo sapiens (Human) 
2022-04-06 | PXD025940 | Pride
Recent approaches of regenerative reproductive medicine investigate the decellularized extracellular matrix to develop a transplantable engineered ovary (TEO). However, a full proteomic analysis is not usually performed after the decellularization process to evaluate the preservation of the extracel...
ORGANISM(S): Bos taurus (Bovine) 
2024-11-15 | PXD052258 | Pride
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