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ProteomicsAMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability
AMPA-type glutamate receptors (AMPARs), key elements in excitatory neuro-transmission in the brain, are macromolecular complexes whose properties and cellular functions are determined by the co-assembled constituents of their proteome. Here we identify AMPAR complexes that transiently form in the en...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2018-10-17 | PXD006413 | Pride
Excitatory synaptic transmission Proteomic analysis Intellectual disability Ampa-receptor biogenesis complexes 
UnknownAMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability.
Not available
S-EPMC5500892 | biostudies-literature
ProteomicsInteractomes of GluA1 and GluA3 subunit containing AMPARs reveal distinct protein composition
The AMPA glutamate receptor (AMPAR) is the major type of synaptic excitatory ionotropic receptor in the brain. The most abundant AMPAR subtypes in the hippocampus are GluA1/2 and GluA2/3 heterotetramers. Each subtype contributes differentially to mechanisms of synaptic plasticity, which may be in pa...
ORGANISM(S): Mus musculus (Mouse) 
2022-12-12 | PXD031603 | Pride
Proteomics Prrt1 Glua1/2 Tarp- γ8 Subcomplexes Ampar Glua2/3 Ms-dap 
UnknownThe Transmembrane Domain Mediates Tetramerization of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors.
Not available
S-EPMC4813562 | biostudies-literature
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