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ProteomicsInteractomes of GluA1 and GluA3 subunit containing AMPARs reveal distinct protein composition
The AMPA glutamate receptor (AMPAR) is the major type of synaptic excitatory ionotropic receptor in the brain. The most abundant AMPAR subtypes in the hippocampus are GluA1/2 and GluA2/3 heterotetramers. Each subtype contributes differentially to mechanisms of synaptic plasticity, which may be in pa...
ORGANISM(S): Mus musculus (Mouse) 
2022-12-12 | PXD031603 | Pride
Proteomics Prrt1 Glua1/2 Tarp- γ8 Subcomplexes Ampar Glua2/3 Ms-dap 
UnknownCollapsin Response Mediator Protein 2 and Endophilin2 Coordinate Regulation of AMPA Receptor GluA1 Subunit Recycling.
Not available
S-EPMC7417516 | biostudies-literature
UnknownC2-lacking isoform of Nedd4-2 regulates excitatory synaptic strength through GluA1 ubiquitination-independent mechanisms.
Not available
S-EPMC6819230 | biostudies-literature
UnknownProline-rich transmembrane protein 2 specifically binds to GluA1 but has no effect on AMPA receptor-mediated synaptic transmission.
Not available
S-EPMC8842155 | biostudies-literature
UnknownMechanisms underlying TARP modulation of the GluA1/2-γ8 AMPA receptor.
Not available
S-EPMC8826358 | biostudies-literature
UnknownSrc homology 2 domain-containing phosphotyrosine phosphatase 2 (Shp2) controls surface GluA1 protein in synaptic homeostasis.
Not available
S-EPMC5602405 | biostudies-literature
Unknownγ-2 and GSG1L bind with comparable affinities to the tetrameric GluA1 core.
Not available
S-EPMC10332039 | biostudies-literature
UnknownArchitecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP γ8.
Not available
S-EPMC6513756 | biostudies-literature
ProteomicsStructure and organisation of AMPA receptor-TARP complexes in the mammalian cerebellum
AMPA receptors (AMPARs) are multimodal transducers of glutamatergic signals throughout the brain. Their diversity is exemplified in the cerebellum, the brain structure integrating sensorimotor information. At afferent synapses, AMPARs mediate high-frequency excitation, while in Bergmann glia (BG) th...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-02-26 | PXD069620 | Pride
Ampa glutamate receptor Mammalian cerebellum Cry-em 
UnknownNeuropilin-2/PlexinA3 Receptors Associate with GluA1 and Mediate Sema3F-Dependent Homeostatic Scaling in Cortical Neurons.
Not available
S-EPMC5726806 | biostudies-literature
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