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UnknownmiR-155 augments CD8+ T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic γc cytokines.
Not available
S-EPMC4299215 | biostudies-literature
UnknownGPX4 overexpressed non-small cell lung cancer cells are sensitive to RSL3-induced ferroptosis.
Not available
S-EPMC10232506 | biostudies-literature
TranscriptomicsMicroRNAs show diverse and dynamic expression patterns in multiple tissues of Bombyx mori
Background: MicroRNAs (miRNAs) repress target genes at the post-transcriptional level, and function in the development and cell-lineage pathways of host species. Tissue-specific expression of miRNAs is highly relevant to their physiological roles in the corresponding tissues. However, to date, few m...
ORGANISM(S): Bombyx mori 
2010-02-20 | E-GEOD-18039 | biostudies-arrayexpress
UnknownBafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Not available
S-EPMC11814099 | biostudies-literature
UnknownNutlin-3a induces KRAS mutant/p53 wild type lung cancer specific methuosis-like cell death that is dependent on GFPT2.
Not available
S-EPMC10720203 | biostudies-literature
ProteomicsClinical characterization and proteomic profiling of lean nonalcoholic fatty liver disease
To investigate the proteomic features in lean subjects with NAFLD, and to identify possible plasma proteins that provide potential application for diagnosing of NAFLD in lean individuals. Participants with or without NAFLD were divided into an overweight NAFLD group, an overweight control group, a l...
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD035514 |
ProteomicsComparison of proteins of Streptococcus suis wild-type and ΔmnmE mutant strains
Streptococcus suis is one of the most important bacterial pathogens of pigs, it is also an important zoonotic pathogen. It can withstand environmental stress and respond rapidly to stress. However, the regulatory mechanisms involved in this process are not fully elucidated. MnmE is a multi-domain GT...
ORGANISM(S): Streptococcus Suis 05zyh33 
2026-04-09 | PXD076839 |
Genomics97dd9532-0482-4bf1-ad1d-fb976b8ed7ea - samples
This dataset contains whole-genome sequencing data files from colon organoid cultures, which were mutated using CRISPR-Cas9 for specific genes (APC, KRAS, TP53 and SMAD4) to generate in vitro transformed cancer cells. After introducing each mutation, the resulting cultures were subjected to whole-ge...
EGAD00001002719 | EGA
GenomicsWhole genome sequencing of colon organoid cultures with artificially induced oncogenic mutations
Using the CRISPR-Cas9 genome editing system, various oncogenic mutations were introduced in the genome of normal adult stem cells derived from the colon. The resulting clonal cultures were subjected to whole genome sequencing. In addition, the cultures were transplanted in a mouse and the resulting ...
EGAS00001001969 | EGA
GenomicsDivision of Biomedical Genetics UMC Utrecht
Data Access Committee EGAC00001000432
EGAC00001000432 | EGA
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