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UnknownEfficacy and safety of PD-1 inhibitors as second-line treatment for advanced squamous esophageal cancer: a systematic review and network meta-analysis with a focus on PD-L1 expression levels.
Not available
S-EPMC11798917 | biostudies-literature
MetabolomicsThe Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis

BACKGROUND: Manchurian walnut (Juglans mandshurica Maxim.) is a tree with multiple industrial uses and medicinal properties in the Juglandaceae family (walnuts and hickories). J. mandshurica produces juglone, which is a toxic allelopathic agent and has potential utilization value...

2022-05-18 | MTBLS3657 | MetaboLights
ProteomicsC. elegans as a model for inter-individual variation in metabolism
Fox BW, Ponomarova O, Lee YU, Zhang G, Giese EG, Walker M, Roberto NM, Na H, Reis-Rodrigues P, Curtis BJ, Kolodziej AR, Crombie TA, Zdraljevic S, Yilmaz LS, Andersen EC, Schroeder FC, Walhout AJM (2022) C. elegans as a model for inter-individual variation in metabolism
ORGANISM(S): Caenorhabditis Elegans (ncbitaxon:6239) 
2021-07-13 | MSV000087810 | MassIVE
UnknownGentianella macrosperma, a new species of Gentianella (Gentianaceae) from Xinjiang, China.
Not available
S-EPMC6728362 | biostudies-literature
GenomicsChIP-seq analysis of LPS trained BMDMs reveals remodeling of Histone 3 Lysine 4 tri-methylation (H3K4me3)
The aim of this study is to profile the distribution of the active histone modification H3K4me3 in BMDMs from WT and SLC1A5_var transgenic mice after low-dose LPS training. We compared the data of ChIP-seq performed on fragmented chromatin immunoprecipitated with anti-H3K4me3 antibody in naive and t...
ORGANISM(S): Mus musculus 
2026-06-24 | E-MTAB-16196 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of LPS-trained bone marrow derived macrophages (BMDMs) reveals altered glutamine and glycolysis metabolic pathways
The aim of this study is to evaluate data by comparing transcriptome profile (RNA-seq) of BMDMs trained with low-dose LPS and untrained BMDMs. Trained immunity enables innate immune cells to acquire memory-like responses, offering a promising strategy to enhance antitumor immunity. However, the meta...
ORGANISM(S): Mus musculus 
2026-06-24 | E-MTAB-16184 | biostudies-arrayexpress
MetabolomicsCD73 inhibitor AB680 suppresses glioblastoma in mice by inhibiting purine metabolism and promoting P2RY12<sup>+</sup> microglia transformation.
CD73 (ecto-5'-nucleotidase) is a metabolic immune checkpoint that dephosphorylates AMP to produce adenosine. Adenosine plays a pivotal role in immunosuppressive tumor microenvironment (TME) through adenosine receptors expressed on various immune cells. AB680, a specific CD73 inhibitor, is currently ...
2025-08-04 | MTBLS11084 | MetaboLights
TranscriptomicsAutotoxicity mechanism of Oryza Sativa: Microarray analysis of rice plants in response to allelochemical ferulic acid
Autotoxicity plays an important mechanism in regulating plant productivity. Ferulic acid (FA) is phytotoxic and was identified in extracts and residues of rice plants as a candidate for rice allelochemicals. To help characterize the autotoxicity mechanism of rice, we present the first large-scale, t...
ORGANISM(S): Oryza sativa 
2013-07-22 | E-GEOD-34899 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse aorta and vSMCs response to dioxin
We compared the global gene expression profiles of C57BL/6 mice aortas with the profiles of cultured vascular smooth muscle cells (vSMC) from the same mice, and determined whether gene responses to dioxin exposure in the vSMCs would be predictive of responses in the aorta.
ORGANISM(S): Mus musculus 
2003-10-29 | E-MEXP-23 | biostudies-arrayexpress
UnknownMolecular modelling of the nucleotide-binding domain of Wilson's disease protein: location of the ATP-binding site, domain dynamics and potential effects of the major disease mutations.
Not available
S-EPMC1133942 | biostudies-literature
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