Anal - OmicsDI

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Unknown (3392)
Proteomics (867)
Transcriptomics (702)
Metabolomics (461)
Genomics (351)
Clinical (159)
Other (8)
Genomic (4)
Methylation profiling (3)
Models (2)
Multiomics (2)

Organisms

Homo sapiens (284)
Mus musculus (200)
Saccharomyces cerevisiae (76)
Drosophila melanogaster (46)
Escherichia coli str. K-12 substr. MG1655 (27)
Rattus norvegicus (26)
Danio rerio (19)
Escherichia coli (15)
Gallus gallus (14)
Canis lupus familiaris (8)
Geobacter sulfurreducens PCA (7)
Sus scrofa (7)
Ciona intestinalis (6)
Schizosaccharomyces pombe (6)
Salmonella enterica subsp. enterica serovar Typhimurium (6)
Xenopus laevis (5)
Bacillus subtilis (5)
Caenorhabditis elegans (5)
Candida albicans (4)
Arabidopsis thaliana (4)
Bombyx mori (3)
Equus caballus (3)
Oryctolagus cuniculus (3)
Bos taurus (3)
Escherichia coli K-12 (3)
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (2)
Camponotus floridanus (2)
Ambystoma mexicanum (2)
Salmonella enterica subsp. enterica serovar Typhimurium str. 14028s Wu (2)
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 (2)

Organisms

Homo sapiens (46)
human gut metagenome (11)
Mus musculus (11)
Danio rerio (6)
Canis lupus familiaris (4)
Escherichia coli (4)
viral metagenome (3)
Proteus mirabilis (3)
Pampus minor (2)
feline metagenome (2)
bovine gut metagenome (2)
gut metagenome (2)
Klebsiella pneumoniae (2)
Rattus norvegicus (2)
unidentified (2)
Zebrasoma scopas (1)
Arcanobacterium buesumense (1)
Escherichia coli O157:H7 str. SS52 (1)
Escherichia coli O157:H7 str. SS17 (1)
Callochromis macrops (1)
Sodalis glossinidius (1)
Molgula (1)
Empedobacter stercoris (1)
Haplochromis burtoni (1)
Parapriacanthus ransonneti (1)
Human papillomavirus (1)
Aphis gossypii (1)
Salmonella enterica subsp. enterica serovar Indiana (1)
Gambusia affinis (1)
bat gut metagenome (1)

Repository

pride (817)
biostudies-arrayexpress (775)
MetaboLights (457)
ENA (221)
geo (44)
EGA (33)
MassIVE (19)
jPOST (12)
GPMDB (5)
iProX (5)
dbGaP (4)
GNPS (4)
BioModels (2)
ExpressionAtlas (1)
PeptideAtlas (1)

Tissue

Cell culture (176)
Epithelial cell (46)
Brain (40)
Blood plasma (30)
Permanent cell line cell (29)
Liver (24)
HeLa cell (22)
Heart (20)
Blood serum (18)
Fibroblast (18)
Blood (17)
Skin (15)
Kidney (14)
Plant cell (14)
Cell suspension culture (12)
T cell (12)
Lung (11)
Whole body (11)
Breast (10)
B cell (8)
Leaf (8)
Blood cell (7)
Cerebrospinal fluid (7)
Urine (7)
Early embryonic cell (6)
Embryo (6)
Hepatocyte (6)
Ileal pouch (1)
Ileum (1)
Plasma Non-glyco (1)

Disease

Breast cancer (22)
Carcinoma (16)
Colorectal Neoplasms (13)
Colorectal cancer (7)
Rectal Neoplasms (6)
Anal Cancer (5)
Colorectal cancer (5)
Neoplasms (5)
Normal (3)
Crohn Disease (3)
Pancreatic Neoplasms (3)
Lung Neoplasms (3)
Colorectal Cancer (3)
Anus Neoplasms (2)
Screening for bowel cancer (2)
Familial adenomatous polyposis (1)
Acute pouchitis (1)
Crohn’s disease-like phenotype (1)
Chronic pouchitis (1)
Primary effusion lymphoma (PEL) (1)
Inflammatory bowel disease (1)
Acute lymphocytic leukemia (1)
Locally advanced breast carcinoma (LABC; non-inflammatory) (1)
Blumeria graminis f.sp. Hordei inoculated (1)
Active Crohn's disease (1)
Kaposi's sarcoma (1)
AIDS-KS, HIV+, nodular (late) stage (1)
Abdominal aortic aneurysm (1)
Rheumatoid arthritis (1)
Locally advanced rectal cancer (1)

Technology Type

Mass Spectrometry (817)
Shotgun proteomics (457)
Mass spectrometry (379)
Bottom-up proteomics (117)
Affinity purification coupled with mass spectrometry proteomics (80)
Gel-based experiment (67)
Data-dependent acquisition (65)
Chemical cross-linking coupled with mass spectrometry proteomics (62)
NMR spectroscopy (55)
Top-down proteomics (40)
Mass spectrometry assay (32)
SWATH MS (24)
SRM/MRM (23)
Data-independent acquisition (19)
HDMSE (12)
MSE (9)
All-ion fragmentation (8)
Mass spectrometry imaging (7)
NMR spectroscopy assay (3)
Affinity proteomics (3)
Glycoproteomics (2)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiSeq 2000 (1)
Immunopeptidomics (1)
Metaproteomics (1)

Instrument Platform

Illumina HiSeq 2000 (30)
NextSeq 500 (30)
Illumina HiSeq 2500 (18)
Illumina NovaSeq 6000 (18)
Illumina HiSeq 4000 (18)
Illumina MiSeq (6)
NextSeq 550 (5)
GenePix 4000A [Axon Instruments] (4)
Vortex (4)
Affymetrix Fluidics Station 400 (3)
ScanArray 4000XL [PerkinElmer] (2)
NextSeq 1000 (2)
Illumina HiSeq 3000 (2)
Using NEBNext Ultra II DNA Library (1)
SnakePipes 3.4 (1)
NEBNext Ultra II DNA Library Prep Kit (1)
10X chemistry 3' v3 (1)
STAR v2.5.3a, rpkmforgenes, RSeQC 2.6.1 (1)
Illumina Nextera XT index kits (Set A–D) (1)
Oligo(dT) primer and SuperScript II reverse transcriptase (ThermoFisher Scientific), TapeStation 4200 or 2100 Bioanalyzer with a DNA High Sensitivity chip (Agilent Biotechnologies) (1)
Aria III (BD Biosciences) (1)
Single nuclei were captured using the 10x Genomics Chromium Controller. (1)
Single cells were captured using the 10x Genomics Chromium Controller. (1)
Computer (1)
Wet Lab (1)
Tissue Culture Lab (1)
GenePix 4000B [Axon] (1)
454 GS FLX (1)
Helicos (1)
None (1)

Publication Date

2022 (231)
2021 (191)
2023 (152)
2024 (149)
2020 (141)
2025 (112)
2026 (112)
2019 (105)
2013 (105)
2014 (100)
2018 (95)
2015 (95)
2010 (93)
2017 (92)
2012 (82)
2011 (81)
2016 (73)
2009 (43)
2008 (36)
2007 (25)
2005 (12)
2006 (10)
2004 (2)

UNIPROT ID/AC

Q9BQG2 (1)
B3KXN9 (1)
Q53HM1 (1)
Q4FEB3 (1)
Q9Y4K0 (1)
Q9HBF5 (1)
Q86SK9 (1)
E9KL42 (1)
Q3I5F7 (1)
P33897 (1)
Q99884 (1)
A8MU28 (1)
P35219 (1)
Q16698 (1)
Q5FC00 (1)
B2RBR4 (1)
Q8WUM9 (1)
Q15274 (1)
Q8WWX8 (1)
Q9NX14 (1)
Q9Y345 (1)
Q86YT5 (1)
Q53H96 (1)
E9PHN8 (1)
Q9NWU1 (1)
B3KT19 (1)
Q96C36 (1)
Q9NP59 (1)
Q9NRX3 (1)
B4DER4 (1)

ENSEMBL ID

ENSG00000170477 (1)

CHEBI ID

CHEBI:27823 (43)
CHEBI:3554 (1)
CHEBI:3338 (1)
CHEBI:3966 (1)
CHEBI:3312 (1)
CHEBI:3313 (1)
CHEBI:3628 (1)
CHEBI:3454 (1)
CHEBI:3544 (1)
CHEBI:4541 (1)
CHEBI:3322 (1)
CHEBI:3729 (1)
CHEBI:3420 (1)
CHEBI:3303 (1)
CHEBI:3339 (1)
CHEBI:58216 (1)
CHEBI:58235 (1)
CHEBI:3793 (1)
CHEBI:58414 (1)
CHEBI:36986 (1)
CHEBI:58052 (1)
CHEBI:57658 (1)
CHEBI:57836 (1)
CHEBI:18402 (1)
CHEBI:57880 (1)
CHEBI:327995 (1)
CHEBI:57367 (1)
CHEBI:57390 (1)
CHEBI:30913 (1)
CHEBI:225237 (1)

Metabolite Name

Glycine (58)
Creatine (56)
Uracil (55)
Taurine (54)
Adenine (53)
Choline (52)
L-Phenylalanine (52)
Hypoxanthine (52)
Creatinine (50)
L-Tyrosine (48)
Citric acid (47)
Phenylalanine (46)
Inosine (46)
Valine (44)
Adenosine (44)
Xanthine (44)
Uridine (44)
Leucine (42)
Guanine (42)
L-Tryptophan (42)
Proline (41)
L-Glutamine (41)
L-Proline (40)
Isoleucine (40)
Tyrosine (39)
Alanine (39)
Tryptophan (39)
L-Threonine (38)
Lysine (38)
Cytosine (38)

First Public Date

2025 (30)
2026 (29)
2023 (25)
2024 (22)
2022 (19)
2021 (19)
2020 (19)
2017 (12)
2019 (11)
2014 (10)
2016 (8)
2013 (7)
2018 (6)
2015 (4)

Modelling Approach

Ordinary differential equation model (1)

Study status

Completed (64)
Recruiting (45)
Not yet recruiting (18)
Terminated (9)
Active, not recruiting (8)
Not provided (8)
Withdrawn (3)
Suspended (2)
Ongoing (1)
Enrolling by invitation (1)

Lab affiliation

Department of Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology and BIOSS Centre for Biological Signalling Studies, University of Freiburg, 79104 Freiburg im Breisgau, Germany (10)
Basic Immune System of Plants / Protein Mass Spectrometry Max Planck Institute for Plant Breeding Research Carl-von-Linne-Weg 10, 50829 Cologne, Germany (9)
Michigan State University (9)
ETH Zurich, Institute of Molecular Systems Biology, Zurich, Switzerland (8)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (7)
Instituto de Biotecnología, Grupo de Bioquímica y Parasitología Molecular, Departamento de Parasitología, Universidad de Granada, Granada, Spain. (6)
State Key Laboratory of Genetic Engineering, Department of Biochemistry, School of Life Sciences, Fudan University, Shanghai 200438, China (6)
Department of Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology and Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104 Freiburg im Breisgau, Germany (5)
Forschungszentrum Juelich GmbH ZEA-3 Analytics Wilhelm-Johnen-Str D-52425 Juelich Germany (5)
CRUK - Beatson Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (4)
Center for Biologics Evaluation and Research (CBER), U.S. Food and Drug Administration (FDA) (4)
Department of Biochemistry and Biomedical Sciences McMaster University (4)
Department of Chemistry & Chemical Biology, Northeastern University (4)
University of Greifswald, Institute of Microbiology, Department of Microbial Proteomics, Felix-Hausdorff-Str. 8, 17489 Greifswald, Germany (4)
University of Wisconsin-Madison (4)
CEA-Marcoule, ProGénoMIX platform, DRF-Li2D, 30207 Bagnols-sur-Cèze, France (3)
Chair of Proteomics and Bioanalytics, Technische Universitaet Muenchen (3)
Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm 17177, Sweden (3)
Georg-August-University Göttingen, Department of Molecular Microbiology and Genetics, Institute of Microbiology and Genetics (3)
Johns Hopkins University (3)
State Key Laboratory of Genetic Engineering, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai 200438, China (3)
University at buffalo, SUNY (3)
Utrecht University (3)
Aarhus University Department of Biomedicine DK-8000 Aarhus C (2)
Abbvie Bioresearch Center (2)
Associate Professor, University of Washington (2)
Barnett Institute of Chemical and Biological Analysis, Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Ave., Boston, Massachusetts 02115, United States (2)
Boston University Medical Campus 670 Albany St., Rm. 509 Boston, MA 02118 USA (2)
Cambridge Institute for Medical Research, Hills Road, Cambridge, CB2 0XY (2)
Cedars-Sinai Medical Center (2)

Keyword

Rectal cancer (5)
Stage IV anal cancer (4)
Recurrent anal cancer (4)
Stage IV gastric cancer (4)
Stage IV pancreatic cancer (4)
Unresectable gallbladder cancer (4)
Colorectal (4)
Pembrolizumab (4)
Recurrent rectal cancer (4)
Recurrent small intestine cancer (3)
Metastatic gastrointestinal carcinoid tumor (3)
Recurrent gastrointestinal carcinoid tumor (3)
Unresectable extrahepatic bile duct cancer (3)
Stage IV esophageal cancer (3)
Advanced adult primary liver cancer (3)
Recurrent gastric cancer (3)
Recurrent pancreatic cancer (3)
Recurrent extrahepatic bile duct cancer (3)
Recurrent gallbladder cancer (3)
Tislelizumab (3)
Ipilimumab (3)
Recurrent colon cancer (3)
Stage IV colon cancer (3)
Stage IV rectal cancer (3)
Nivolumab (3)
Irinotecan (3)
Immunotherapy (3)
Fluorouracil (3)
Stage III rectal cancer (3)
Inoperable (2)

IsPrivate

False (2)

Model Flag

Non Kinetic (1)

Submitter Keywords

Immuno-oncology (1)

Classification

bacteria (15)
viruses (3)
fungi (1)

Modification

15.994915 (5)
57.021464 (5)
42.010565 (3)
N6 (3)
3x(2)H labeled N6-acetyl-L-lysine (2)
Not available (2)
-17.026549 (1)
-18.010565 (1)
4x(15)N labeled L-arginine (1)
6x(2)H labeled dimethylated L-arginine (1)
79.966331 (1)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (349)
Interventional (117)
RNA-seq of coding RNA (95)
ChIP-seq (86)
ChIP-chip by tiling array (71)
ChIP-chip by array (38)
Observational (38)
Comparative genomic hybridization by array (21)
RNA-seq of coding RNA from single cells (20)
Unknown experiment type (12)
Other (12)
RNA-seq of non coding RNA (12)
Proteomic profiling by array (10)
Transcription profiling by tiling array (9)
High-throughput sequencing (5)
DNA-seq (5)
Animal - High-throughput sequencing (4)
Antigen profiling (4)
Spatial transcriptomics by high-throughput sequencing (3)
ATAC-seq (3)
Transcription profiling by SAGE (2)
Genotyping by array (2)
Single nucleus RNA sequencing (2)
RNA-seq of total RNA (2)
Human - One-color microarray (1)
Cell line - High-throughput sequencing (1)
Transcription profiling by RT-PCR (1)
MicroRNA profiling by array (1)
Methylation profiling by array (1)
CUT&RUN (1)

Release Date

2025 (418)
2022 (418)
2023 (414)
2024 (370)
2020 (342)
2021 (339)
2019 (253)
2018 (206)
2015 (183)
2014 (172)
2017 (166)
2013 (161)
2016 (145)
2010 (117)
2012 (114)
2011 (109)
2026 (71)
2009 (50)
2008 (45)
2007 (30)
2006 (16)
2005 (15)
2004 (6)
2001 (3)
2002 (2)
1999 (2)

Location

United States (46)
Australia (45)
Germany (16)
China (15)
United Kingdom (11)
France (10)
Iran (8)
India (8)
New Zealand (5)
Denmark (5)
Italy (5)
Spain (5)
Belgium (4)
Canada (4)
Netherlands (4)
Japan (4)
Taiwan (3)
Brazil (3)
Norway (2)
Egypt (2)
Africa (1)
Oceania (1)
South America (1)
Guam (1)
Serbia (1)
South Africa (1)
Hong Kong (1)
Ireland (1)
Philippines (1)
Singapore (1)

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Anal Canal Cancer : subclassification

Etiologically linked to HPV infection, malignancies of the anal canal have substantially increased in incidence over the last 20 years. Although most anal squamous cell carcinomas (SCC) respond well to chemoradiotherapy, for undetermined reasons, a subgroup of patients experience a poor outcome. Des...

ORGANISM(S): Homo sapiens (Human)

2016-12-20 | PXD004859 | Pride

Utility of CYP2D6 copy number variants as prognostic biomarker in localized anal squamous cell carcinoma

Anal squamous cell carcinoma (ASCC) is an infrequent tumor. Since 70s, treatment of stages II-III consists on a combination of 5-fluorouracil (5FU), mitomycin C (MMC), and radiotherapy. The aim of this study is the identification of biomarkers that allow personalized treatment and improvement of the...

ORGANISM(S): Homo sapiens (Human)

2023-04-26 | PXD037816 | Pride

Ascc Dia Anal squamous cell carcinoma Ffpe Radiotherapy 5fu Mmc Lc-ms/ms

Pet anal swab

Pet anal swab Raw sequence reads

PRJNA1332161 | ENA

Genome-Wide Host Methylation Profiling of Anal and Cervical Carcinoma [anal]

PRJNA776338 | ENA

Clostridium perfringens strain:Human anal swab | isolate:Human anal swab

Clostridium perfringens strain:Human anal swab | isolate:Human anal swab Genome sequencing

PRJNA1067801 | ENA

Microbiome biomarkers for Improved Screening of Anal Cance

Anal cancer is a leading neoplasia in people with immune impartments populations, and the lack of an accurate screening test challenges its prevention. Because the bacteria living in the anal epithelium the anal microbiota seems to influence and be influenced by cancer development, specific patterns...

ORGANISM(S): Homo sapiens (Human)

2022-12-11 | PXD037268 | Pride

Cancer Microbiome Human

Genome-Wide Host Methylation Profiling of Anal and Cervical Carcinoma [anal]

HPV infection results in changes in host gene methylation which, in turn, are thought to contribute to the neoplastic progression of HPV-associated cancers. The objective of this study was to identify joint and disease-specific genome-wide methylation changes in anal and cervical cancer as well as c...

ORGANISM(S): Homo sapiens

2021-11-29 | GSE186858 | GEO

anal swab

anal swab Raw sequence reads

PRJNA1017976 | ENA

SCRAtCH -Microbiota-based SCReening of Anal Cancer in HIV-infected individuals

Harnessing the Microbiota to Discover Biomarkers of Precancerous Anal Lesions in People with HIV

PRJEB58898 | ENA

Transcriptome and microbiome-immune changes across preinvasive and invasive anal cancer lesions

PRJNA1066280 | ENA

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