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ProteomicsIdentification of cellular CDK9 substrates using an analog-sensitive cell line
Analog-sensitive kinase technology allows for specific inhibition of a given kinase. Here we utilize an analog-sensitive CDK9 cell line to determine the impact of CDK9 inhibition on the phospho-proteome of human cells. Specifically, we aim to identify substrates of CDK9 in a quantitative way using s...
ORGANISM(S): Homo sapiens (Human) 
2019-11-11 | PXD014825 | Pride
Analog-sensitive Mass spectrometry P-tefb Protein phosphorylation 
ProteomicsIdentification of RSK substrates using an analog-sensitive kinase approach
RSK1 and RSK4 are two of the four members of the p90 ribosomal protein S6 kinases (RSK) family. These kinases are downstream kinases of mitogen-activated protein kinase 1 (ERK or MAPK1) in the ERK MAP kinase pathway. RSKs are implicated in fine tuning of cellular processes such as translation, trans...
ORGANISM(S): Homo sapiens (Human) 
2024-02-06 | PXD047020 | Pride
Rsk1 Rsk4 Mapk pathway Kinase Substrate 
UnknownIdentification of RSK substrates using an analog-sensitive kinase approach.
Not available
S-EPMC10945272 | biostudies-literature
UnknownRecombinant Human Cytomegalovirus Expressing an Analog-Sensitive Kinase pUL97 as Novel Tool for Functional Analyses.
Not available
S-EPMC9610083 | biostudies-literature
UnknownStructure-guided inhibitor design expands the scope of analog-sensitive kinase technology.
Not available
S-EPMC3938192 | biostudies-literature
UnknownModulation of plant growth in vivo and identification of kinase substrates using an analog-sensitive variant of CYCLIN-DEPENDENT KINASE A;1.
Not available
S-EPMC5037886 | biostudies-literature
UnknownATP analog-sensitive Pat1 protein kinase for synchronous fission yeast meiosis at physiological temperature.
Not available
S-EPMC3341230 | biostudies-literature
ProteomicsProteome after 3MB-PP1 treatment
The human cytomegalovirus (HCMV) is a member of the beta-herpesvirus family and inflicts life-long latent infections in its hosts. HCMV has been shown to manipulate and dysregulate many cellular processes. On major interactor with the cellular host is the viral kinase pUL97. The UL97 gene is essenti...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD036455 | Pride
Human Tmt 
UnknownInhibition of ZAP-70 kinase activity via an analog-sensitive allele blocks T cell receptor and CD28 superagonist signaling.
Not available
S-EPMC2397475 | biostudies-literature
GenomicsPol II and CTD Phosphorylation ChIP-chip of ATP-analog sensitive Kin28 budding yeast
Pol II and CTD Phosphorylation ChIP-chip of ATP-analog sensitive Kin28 budding yeast
PRJNA325831 | ENA
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