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ProteomicsProteomics analysis of iPSCs and iPSCs-derived hepatocytes carrying MIC13 pathogenic variant.
MIC13-related mitochondrial hepato-encephalopathy is a rare mitochondrial disorder associated with multisystem involvement, including liver failure. To better understand the molecular consequences of MIC13 deficiency, we generated induced pluripotent stem cells (iPSCs) carrying MIC13 pathogenic vari...
ORGANISM(S): Homo sapiens (Human) 
2026-09-11 | PXD072091 | Pride
Induced pluripotent stem cells Induced hepatocytes Liver failure Mitochondrial disease 
ProteomicsThe interactome of human MIC13, a subunit of MICOS complex
Description: MIC13 is a subunit of the mitochondrial contact site and cristae organizing system (MICOS) and essential for mitochondrial cristae structure. Here we enriched Mic13 by co-Immunoprecipitation and identified interacting proteins.
ORGANISM(S): Homo sapiens (Human) 
2025-01-02 | PXD044968 | Pride
Micos Mib Mitochondria Lc-msms 
TranscriptomicsAn Ets2-specific transcriptional program in tumor-associated macrophages promotes metastasis
Macrophages have been implicated in breast cancer progression and metastasis, but relatively little is known about the genes and pathways that are involved. Using a conditional allele of Ets2 in the mouse, we have identified Ets2 as a critical gene in tumor associated macrophages (TAMs) that specif...
ORGANISM(S): Mus musculus 
2010-01-05 | E-GEOD-12863 | biostudies-arrayexpress
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