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GenomicsAnaphase-promoting complex-dependent control of cell identity
Anaphase-promoting complex-dependent control of cell identity
PRJNA504508 | ENA
GenomicsClinical treatment responsiveness in recurrent canine lymphoma correlates with Anaphase Promoting Complex activity ​
Clinical treatment responsiveness in recurrent canine lymphoma correlates with Anaphase Promoting Complex activity ​
PRJNA496432 | ENA
GenomicsThe Anaphase Promoting Complex/Cyclosome degrades DMS3 to maintain RNA-directed DNA Methylation in Arabidopsis [lncRNA-seq]
The Anaphase Promoting Complex/Cyclosome degrades DMS3 to maintain RNA-directed DNA Methylation in Arabidopsis [lncRNA-seq]
PRJNA418706 | ENA
GenomicsThe Anaphase Promoting Complex/Cyclosome degrades DMS3 to maintain RNA-directed DNA Methylation in Arabidopsis [small RNA-seq]
The Anaphase Promoting Complex/Cyclosome degrades DMS3 to maintain RNA-directed DNA Methylation in Arabidopsis [small RNA-seq]
PRJNA418705 | ENA
TranscriptomicsRNAi profiling by array of human U202 cells with Cdh1shRNA knockdown to identify candidate interacting or target proteins of the anaphase-promoting complex_cyclosome
U2OS cells were transduced by a lentiviral vector carrying a Cdh1 shRNA and a puromycin resistance gene for selection. A vector carrying a GFP shRNA was used as control. The cells were stored in liquid N2 within 10 days after transduction in order to minimize the number of passages. Cells were thawe...
ORGANISM(S): Homo sapiens 
2010-09-10 | E-MEXP-2860 | biostudies-arrayexpress
ProteomicsSUMO targets the APC/C in a phosphorylation-dependent manner to regulate transition from metaphase to anaphase
Signal transduction by Small Ubiquitin-like Modifier (SUMO) regulates a myriad of nuclear processes. Here, we report on the role of SUMO in mitosis in human cell lines. Knocking down the SUMO conjugation machinery resulted in a delay in mitosis and defects in mitotic chromosome separation. Searching...
ORGANISM(S): Homo sapiens (Human) 
2018-09-19 | PXD006335 | Pride
Anaphase promoting complex Apc4 Sumo Mitosis Phosphorylation Chromatin bridges Kif18b Ubiquitin 
ProteomicsLactate regulates cell cycle and proliferation by remodeling the anaphase promoting complex
Lactate is abundant in rapidly dividing cells, due to the requirement for elevated glucose catabolism to support proliferation. However, it is not known whether accumulated lactate affects the proliferative state. Here, we deploy a systematic approach to determine lactate-dependent regulation of pro...
ORGANISM(S): Homo sapiens (Human) 
2023-02-07 | PXD036641 | Pride
Tpp Lactate Cell cycle 
UnknownStructure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex.
Not available
S-EPMC2989460 | biostudies-literature
UnknownThe Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex.
Not available
S-EPMC21538 | biostudies-literature
GenomicsAnaphase-promoting complex-dependent control of cell identity
Tissue development and homeostasis rely on the proliferation of progenitor cells, whose identities are established by tightly controlled gene expression networks. However, mRNA synthesis is inhibited during mitosis, and the transcriptional programs that define a cell type must be restarted upon entr...
ORGANISM(S): Homo sapiens 
2020-02-03 | GSE122298 | GEO
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