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MetabolomicsMetabolomic and Proteomic Stratification of Equine Osteoarthritis

Osteoarthritis (OA) is characterised by loss of articular cartilage, synovial membrane dysfunction and subchondral sclerosis. Few studies have used a global approach to stratify equine synovial fluid (SF) molecular profiles according to OA severity. SF was collected from 58 metacarpophalangeal (M...

2025-10-16 | MTBLS1645 | MetaboLights
TranscriptomicsThe effects of NAC on gene expression in Nkx3.1-/- mouse prostate
We tested the effects of the antioxidant NAC (N-Acetyl-Cysteine) on gene expression in Nkx3.1-deficient mouse prostate. Mice that were homozygous null for Nkx3.1 were given NAC or plain water ad libidum for 13 weeks after weaning. Prostates were collected, RNA was harvested and reverse transcribed, ...
ORGANISM(S): Mus musculus 
2012-10-23 | E-GEOD-40352 | biostudies-arrayexpress
TranscriptomicsEffect of AZD1208 on gene expression in recurrent resistant Myc-CaP tumors grown in castrated mice.
AZD1208 is a novel PIM kinase inhibitor that we have shown inhibits tumorigenesis in tissue recombination models, Myc-CaP allograft models, and human prostate cancer xenografts. We sought to determine the intracellular pathways that are responsible for the anti-tumor effect. To this end we used the ...
ORGANISM(S): Mus musculus 
2014-12-24 | E-GEOD-59106 | biostudies-arrayexpress
GenomicsChIP-Seq for Nkx3-1 in whole mouse prostate
We report the genome-wide binding sites of the NK homeodomain transcription factor, Nkx3-1, in mouse prostate. Three different mouse genotypes were used: Nkx3-1 wild-type (WT), Nkx3-1 heterozygote (HET), and Nkx3-1 knock-out (KO). Two biological replicates were performed for WT and HET, and one repl...
ORGANISM(S): Mus musculus 
2012-04-09 | E-GEOD-35971 | biostudies-arrayexpress
UnknownPrediction of disability-free survival in healthy older people.
Not available
S-EPMC9213595 | biostudies-literature
UnknownEffect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly.
Not available
S-EPMC6289056 | biostudies-literature
UnknownEffect of Aspirin on Disability-free Survival in the Healthy Elderly.
Not available
S-EPMC6426126 | biostudies-literature
UnknownEffect of Aspirin on All-Cause Mortality in the Healthy Elderly.
Not available
S-EPMC6433466 | biostudies-literature
UnknownSurgical outcomes from haematoma evacuation for intracerebral haemorrhage in the INTERACT3 study.
Not available
S-EPMC12414919 | biostudies-literature
UnknownThe third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial.
Not available
S-EPMC10401723 | biostudies-literature
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