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MetabolomicsIdentifying metabolic alterations associated with coral growth anomalies using 1H NMR metabolomics
Coral growth anomalies (GAs) are tumor-like protrusions that are detrimental to coral health, impacting both the coral skeleton and soft tissues. These lesions are increasingly found throughout the tropics and are commonly associated with high human population density, yet little is known about the ...
2021-06-15 | MTBLS2424 | MetaboLights
MetabolomicsEvaluation of Sample Preparation Methods for the Analysis of Reef-Building Corals Using 1H-NMR-based Metabolomics
The field of metabolomics generally lacks standardized methods for the preparation of samples prior to analysis. This is especially true for metabolomics of reef-building corals, where the handful of studies that have been published employ a range of sample preparation protocols. The utilization of ...
2019-03-20 | MTBLS862 | MetaboLights
TranscriptomicsMultinucleated Tartrate Resistant Acid Phosphatase Positive Cells with Macrophage and Osteoclast Phenotypes in Bone
Prothrombin (PT) and osteopontin (OPN) promotes adhesion of different TRAP-positive multinucleated cells isolated from rat long bone (Hu et al. Exp Cell Res. 2008; 314: 638-50). The PT-adhering cell could represent either an immature precursor to the OPN-adherent osteoclast or constitute a distinct...
ORGANISM(S): Rattus norvegicus 
2010-12-31 | E-GEOD-19950 | biostudies-arrayexpress
UnknownNationwide implementation of minimally invasive liver surgery: population-based analysis.
Not available
S-EPMC12822779 | biostudies-literature
MetabolomicsGrazer-induced transcriptomic and metabolomic response of the chain-forming diatom Skeletonema marinoi
Diatoms and copepods are main actors in marine food webs. The prey-predator interactions between them affect bloom dynamics, shape marine ecosystems and impact the energy transfer to higher trophic levels. Recently it has been demonstrated that the presence of grazers may affect the diatom prey beyo...
2018-10-23 | MTBLS571 | MetaboLights
TranscriptomicsPolyunsaturated dietary fats decrease mortality and bacterial load during septic S. aureus infection, and improve neutrophil function in mice
Severe infections and sepsis is an increasing clinical problem that cause prolonged morbidity and substantial mortality. At present, antibiotics are essentially the only pharmacological treatment for sepsis. The incidence of antibiotic resistance is increasing and it is therefore critical to find ne...
ORGANISM(S): Mus musculus 
2014-11-24 | E-GEOD-58358 | biostudies-arrayexpress
UnknownSex differences and risk factors for bleeding in Alagille syndrome.
Not available
S-EPMC9728057 | biostudies-literature
TranscriptomicsTranscription profiling of human joint tissue using multiple biopsies taken from the same knee
Analysis of intra- and inter variation using multiple biopsies taken from the same knee. The biopsies were obtained from thirteen different patients; seven by orthopedic surgery and six by rheumatic arthroscopy. Orthopedic samples (patients 1-7 Three synovial tissue specimens were obtained from ran...
ORGANISM(S): Homo sapiens 
2005-06-22 | E-MEXP-367 | biostudies-arrayexpress
TranscriptomicsAnalysis of the DNA methylome and transcriptome in granulopoiesis reveal timed changes and dynamic enhancer methylation [expression]
The study investigated the changes in DNA-methylation and gene expression during granulopoiesis. To this end CMP, GMP, PMC and PMN cell populations were isolated by FACS from bonemarrow from healty donors and analysed by CAGE as well as expression and DNA microarrays total RNA was isolated from CMP,...
ORGANISM(S): Homo sapiens 
2014-04-29 | E-GEOD-49883 | biostudies-arrayexpress
TranscriptomicsAnalysis of the DNA methylome and transcriptome in granulopoiesis reveal timed changes and dynamic enhancer methylation
The study investigated the changes in DNA-methylation and gene expression during granulopoiesis. To this end CMP, GMP, PMC and PMN cell populations were isolated by FACS from bone marrow from healthy donors and analysed by CAGE as well as expression and DNA microarrays. Bisulphite converted DNA from...
ORGANISM(S): Homo sapiens 
2014-03-27 | E-GEOD-50797 | biostudies-arrayexpress
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