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Endothelial cells control muscle regeneration through angiocrine lactate
Recently, we have shown that after partial hepatectomy (PHx), an increased hepatic blood flow initiates liver growth in mice by vasodilation and mechanically-triggered release of angiocrine signals. Here, we use mass spectrometry to identify a mechanically-induced angiocrine signal in human hepatic ...
ORGANISM(S): Homo sapiens (Human) 
2023-12-28 | PXD033942 | Pride
Endothelial cells were transduced with different genes modulating signaling pathways and compared to GFP transduced control group to identify changes in the expression of the angiocrine factors. The experiment compared endothelial genetic changes upon Akt, MAP kinase and PymT activation.
ORGANISM(S): Homo sapiens 
Endothelial H2S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis
Microvascular endothelial cells (EC) display a high degree of phenotypic and functional heterogeneity among different organs. Organ-specific EC control their tissue microenvironment by angiocrine factors in health and disease. Liver sinusoidal EC (LSEC) are uniquely differentiated to fulfil importan...
ORGANISM(S): Mus musculus 
2017-01-31 | GSE90506 | GEO
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