Animal-free - OmicsDI

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Unknown (3983)
Transcriptomics (1951)
Genomics (650)
Proteomics (269)
Metabolomics (132)
Other (4)
Models (3)
Methylation profiling (3)
Clinical (2)
Genomic (1)

Organisms

Mus musculus (891)
Homo sapiens (346)
Rattus norvegicus (238)
Sus scrofa (63)
Bos taurus (59)
Drosophila melanogaster (55)
Caenorhabditis elegans (46)
Gallus gallus (37)
Arabidopsis thaliana (33)
Danio rerio (29)
Saccharomyces cerevisiae (16)
Canis lupus familiaris (15)
Ovis aries (13)
Escherichia coli (11)
Macaca mulatta (10)
Chlorocebus sabaeus (9)
Xenopus laevis (8)
Macaca fascicularis (8)
Oncorhynchus mykiss (8)
Escherichia coli str. K-12 substr. MG1655 (8)
Daphnia magna (6)
Streptomyces coelicolor (5)
Bacteroides thetaiotaomicron (4)
Mus musculus domesticus (4)
mouse gut metagenome (4)
Apis mellifera (4)
Zea mays (4)
Salmo salar (4)
Salvelinus leucomaenis (1)
Oncorhynchus masou masou (1)

Organisms

Mus musculus (159)
Homo sapiens (59)
Rattus norvegicus (38)
Sus scrofa (20)
Bos taurus (10)
Drosophila melanogaster (9)
Ovis aries (5)
Arabidopsis thaliana (5)
mouse gut metagenome (5)
Canis lupus familiaris (4)
Capra hircus (4)
Gallus gallus (4)
Macaca fascicularis (3)
Salpingoeca rosetta (2)
Xenopus laevis (2)
Cryptococcus neoformans (2)
Callithrix jacchus (2)
bovine gut metagenome (2)
rat gut metagenome (2)
Limosilactobacillus reuteri (2)
Macaca mulatta (2)
Danio rerio (2)
Oceanispirochaeta crateris (1)
Sphaeroforma sirkka (1)
Mycobacterium avium subsp. paratuberculosis K-10 (1)
Bombus terrestris audax (1)
Papio hamadryas (1)
Spongilla lacustris (1)
Theileria parva (1)
Symbiopectobacterium purcellii (1)

Repository

biostudies-arrayexpress (1954)
ENA (536)
pride (176)
MetaboLights (130)
geo (118)
MassIVE (43)
jPOST (26)
iProX (15)
EGA (12)
PanoramaPublic (5)
BioModels (3)
PAXDB (3)
GNPS (2)
dbGaP (1)
NODE (1)

Tissue

Brain (24)
Cell culture (16)
Liver (13)
Heart (9)
Blood serum (8)
Kidney (8)
Whole body (6)
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Blood plasma (4)
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Skin (4)
Testis (4)
Abdominal adipose tissue (3)
Blood (3)
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Early embryonic cell (3)
Skeletal muscle (3)
Somatic cell (3)
Stem cell (3)
Tooth enamel (3)
Animal cap (2)
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Cerebrospinal fluid (2)
Enamel (2)
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Hepatocyte (2)
Hypothalamus (2)
Macrophage (2)
Fecal (1)

Disease

Normal (15)
Alzheimer's disease (5)
Adenocarcinoma (3)
Breast adenocarcinoma (2)
Chronic myeloid leukemia (2)
H9N2 infected (2)
Retinoblastoma (1)
Diabetes mellitus type 1 (1)
Hepatomegaly (1)
T. circumcincta infection (1)
Multibacillary (1)
Liver cancer (1)
Autoimmune disorder (1)
Not applicable (1)
Asthma (1)
Embryonic lethal at day 8.5 to 9.5 (1)
Ischaemia reperfusion injury (1)
Infected with IBDV strain F52/70 (1)
B. dendrobatidis infection (1)
Cutaneous melanoma (1)
Folate deficiency (1)
Imatinib-resistant CML cell line subclone (1)
No injury (1)
Systemic juvenile idiopathic arthritis (1)
Pancreatic ductal adenocarcinoma (1)
Dystrophic (1)
Infected (1)
Oligodendroglioma (1)
Sham treated (1)
Malignant fibrous histiocytoma (1)

Technology Type

Mass Spectrometry (176)
Shotgun proteomics (116)
Mass spectrometry (100)
Bottom-up proteomics (35)
Mass spectrometry assay (23)
Data-dependent acquisition (13)
Data-independent acquisition (10)
SWATH MS (9)
NMR spectroscopy (8)
Gel-based experiment (8)
Affinity purification coupled with mass spectrometry proteomics (7)
Top-down proteomics (7)
HDMSE (4)
SRM/MRM (3)
Aperio (1)
All-ion fragmentation (1)
DiaPASEF (1)
Glycoproteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (45)
Illumina HiSeq 2500 (44)
NextSeq 500 (44)
Illumina HiSeq 2000 (43)
Illumina HiSeq 4000 (24)
Illumina MiSeq (14)
NextSeq 2000 (9)
Axon GenePix 4000B scanning hardware (8)
Illumina HiSeq 1500 (7)
Illumina Genome Analyzer IIx (6)
ScanArray 5000 [PerkinElmer] (5)
Illumina Genome Analyzer II (5)
Illumina NovaSeq X (5)
Genepix (4)
G2565AA DNA microarray scanner [Agilent] (4)
G2565BA DNA microarray scanner [Agilent] (4)
Scanning hardware (4)
NextSeq 550 (4)
Illumina HiSeq 3000 (4)
Agilent high resolution C scanner (3)
GenePix Professional 4200A [Axon Instruments] (3)
GenePix 4000A [Axon Instruments] (3)
Agilent High resolution C scanner (2)
Affymetrix GeneChip Scanner 3000 7G (2)
Illumina HiScanSQ (2)
Agilent 2100 Bioanalyzer (2)
Agilent G2565BA (2)
Illumina Genome Analyzer (2)
GenePix Personal 4100A [Axon Instruments] (2)
Other (2)

Publication Date

2010 (215)
2013 (213)
2015 (205)
2014 (201)
2012 (170)
2011 (154)
2008 (129)
2009 (124)
2016 (122)
2024 (92)
2025 (91)
2021 (91)
2022 (90)
2023 (77)
2007 (72)
2020 (71)
2017 (69)
2018 (64)
2019 (60)
2005 (56)
2026 (51)
2006 (26)
2004 (12)
2003 (11)
2002 (1)

UNIPROT ID/AC

128UP_DROME (1)
140U_DROME (1)
1433B_HUMAN (1)
1433E_DROME (1)
1433E_HUMAN (1)
1433F_HUMAN (1)
1433G_HUMAN (1)
1433S_HUMAN (1)
1433T_HUMAN (1)
1433Z_DROME (1)
1433Z_HUMAN (1)
18C_DROME (1)
2AAA_DROME (1)
2AAA_HUMAN (1)
2AAB_HUMAN (1)
2ABA_DROME (1)
2ABA_HUMAN (1)
2ABB_HUMAN (1)
2ABD_HUMAN (1)
3HIDH_DROME (1)
3HIDH_HUMAN (1)
41_DROME (1)
5HT1R_DROME (1)
5HT2A_DROME (1)
5HT2B_DROME (1)
5NT3B_DROME (1)
5NTC_HUMAN (1)
6PGD_DROME (1)
6PGD_HUMAN (1)
6PGL_DROME (1)

CHEBI ID

CHEBI:15891 (36)
CHEBI:16704 (35)
CHEBI:16919 (35)
CHEBI:17368 (35)
CHEBI:16750 (32)
CHEBI:15741 (32)
CHEBI:17568 (32)
CHEBI:15428 (31)
CHEBI:17596 (31)
CHEBI:16708 (30)
CHEBI:6650 (29)
CHEBI:17154 (29)
CHEBI:16335 (29)
CHEBI:32816 (29)
CHEBI:16737 (29)
CHEBI:30769 (29)
CHEBI:16359 (28)
CHEBI:17562 (27)
CHEBI:7916 (27)
CHEBI:17895 (27)
CHEBI:16811 (26)
CHEBI:17748 (26)
CHEBI:17821 (26)
CHEBI:18012 (26)
CHEBI:30915 (26)
CHEBI:15354 (26)
CHEBI:48430 (25)
CHEBI:18237 (25)
CHEBI:18257 (25)
CHEBI:25017 (25)

Metabolite Name

Taurine (25)
Hypoxanthine (23)
Uridine (22)
Inosine (22)
Thymine (21)
Guanosine (21)
Creatine (19)
L-Tyrosine (19)
Uracil (18)
Cholic acid (18)
Creatinine (18)
L-Phenylalanine (18)
Ornithine (17)
Deoxycholic acid (17)
Xanthine (17)
L-Histidine (16)
Adenosine (16)
Palmitic acid (16)
Linoleic acid (16)
L-Glutamine (16)
Thymidine (16)
L-Proline (15)
L-Tryptophan (15)
Adenine (15)
Cytidine (15)
L-Valine (15)
L-Methionine (15)
Betaine (14)
L-Lysine (14)
L-Arginine (14)

First Public Date

2014 (105)
2025 (72)
2024 (69)
2026 (48)
2023 (41)
2020 (34)
2019 (34)
2021 (31)
2022 (26)
2015 (21)
2018 (19)
2017 (17)
2013 (12)
2016 (6)
2010 (1)

Modelling Approach

Dynamical characteristic (1)
Spatial characteristic (1)
Differential equation model (1)
Ordinary differential equation model (1)

Study status

Not provided (1)
Recruiting (1)

Lab affiliation

Acupuncture and Tuina School/Third Teaching Hospital, Chengdu University of Traditional Chinese Medicine (2)
College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University (2)
Department of Biology, University of Bergen, Bergen, Norway (2)
Department of Veterinary Biosciences, Melbourne Veterinary School, The University of Melbourne, Parkville, Victoria 3010, Australia (2)
Departments of Biochemistry and Neurology Emory University School of Medicine (2)
MPIs for Biophysics and Brain Research (2)
MSAP UAR 3290 CNRS (2)
Molecular Biosciences and the Center for Systems and Synthetic Biology, The University of Texas at Austin, Austin, TX USA (2)
Research Officer|Proteomics and Small Molecule Mass Spectrometry Laboratory | Central Analytical Research Facility (CARF)| Queensland University of Technology | Address: Level 6, P Block, Gardens Point Campus, 2 George St Brisbane QLD 4000 (2)
1 Joint International Research Laboratory of Agriculture and Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu225009, P.R. China 2 Key Laboratory of Animal Breeding Reproduction and Molecular Design for Jiangsu Province, College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu225009, P.R. China (1)
Associate Professor in Molecular Biopharmaceutics, Department of Pharmacy, Uppsala University, Uppsala, Sweden (1)
Associate professor, Department of Biomedical laboratory sciences and chemical engineering, Bergen University College, Bergen, Norway. (1)
BK21 Plus KNU Multi-Omics-based Creative Drug Research Team, College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Republic of Korea (1)
Biological Mass Spectrometry Lab,Department of Translational Medicine (DiMeT),Center for Translational Research on Autoimmune & Allergic Diseases - CAAD,University of Piemonte Orientale, Corso Trieste 15/A, 28100, Novara, Italy (1)
Biomedical Research Centre, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic (1)
Bioprocessing Technology Institute , Agency for Science, Technology and Research-A*STAR, 20 Biopolis Way 06-01, Singapore 138668, Republic of Singapore (1)
CSIRO Food Futures National Research Flagship, Division of Livestock Industries, Queensland Biosciences Precinct, St. Lucia, Queensland, Australia (1)
Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK (1)
Cellular Proteome Research, Helmholtz-Centre for Infection Research, Braunschweig, Germany (1)
Center for Excellence in Vascular Biology, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA (1)
Center for Diagbostik, Institute of Neuropathology, University Medical Center Hamburg Eppendorf, Germany (1)
Center for Environmental and Human Toxicology Department of Physiological Sciences & College of Medicine College of Veterinary Medicine University of Florida (1)
Center for Research Innovation and Bioinformatics, Faculty of Medical Technology, Mahidol University, Nakhon Pathom, Thailand (1)
Centre for Applied Pharmacokinetic Research, School of Health Sciences, The University of Manchester. (1)
Centre for Bioinnovation, University of the Sunshine Coast (1)
Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona 08003, Spain (1)
Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, 3168, Australia. (1)
Charles Perkins Centre, School of Life and Environmental Sciences, University of Sydney, Camperdown, NSW, Australia. (1)
China Medical University School of Forensic Medicine (1)
Chinese Academy of Inspection and Quarantine (1)

Keyword

Beta-blocker (1)
COX-2 inhibitor (1)
UFUR (1)
Etodolac (1)
Propranolol (1)
Thalidomide (1)
Oxaliplatin (1)

IsPrivate

False (3)

Classification

bacteria (5)
fungi (2)
protozoa (1)

Modification

2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)

Study type

Transcription profiling by array (1310)
RNA-seq of coding RNA (271)
ChIP-seq (64)
RNA-seq of non coding RNA (38)
Unknown experiment type (32)
Other (26)
RNA-seq of coding RNA from single cells (20)
Methylation profiling by high throughput sequencing (19)
Comparative genomic hybridization by array (18)
Animal - High-throughput sequencing (17)
ChIP-chip by array (17)
DNA-seq (11)
Cell line - High-throughput sequencing (9)
Ribo-seq (9)
Animal - One-color microarray (8)
ChIP-chip by tiling array (8)
Methylation profiling by array (8)
Transcription profiling by tiling array (7)
RNA-seq of total RNA (7)
Transcription profiling by SAGE (5)
High-throughput sequencing (5)
Human - High-throughput sequencing (4)
MicroRNA profiling by array (4)
Genotyping by array (3)
ATAC-seq (3)
Animal - Two-color microarray (2)
Animal - Single-cell sequencing (2)
Cell line - One-color microarray (2)
Transcription profiling by RT-PCR (2)
MicroRNA profiling by high throughput sequencing (2)

Release Date

2023 (489)
2022 (483)
2021 (454)
2025 (408)
2024 (367)
2020 (363)
2019 (337)
2015 (332)
2013 (298)
2014 (296)
2016 (279)
2018 (272)
2017 (259)
2010 (252)
2012 (232)
2011 (200)
2009 (154)
2008 (154)
2007 (85)
2005 (65)
2026 (59)
2006 (45)
2004 (21)
2003 (10)
2002 (10)
2000 (5)
2001 (4)
1999 (2)
1998 (1)
1995 (1)

Location

Taiwan (1)
Israel (1)

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Animal product-free culture conditions for 3D primary human hepatocyte spheroids improve long-term viability and drug metabolism

3D cultures of primary human hepatocytes (3D PHH) are successfully used to reduce and replace the use of animal experiments in biomedical research. Yet, the initial formation of 3D PHH is highly dependent on the supplementation with fetal bovine serum (FBS). However, the molecular composition of FBS...

ORGANISM(S): Homo sapiens (Human)

2026-01-23 | PXD056428 | Pride

Enhanced immune response of human iPSC-macrophages via animal-free manufacturing processes

PRJNA1368751 | ENA

Policy driven changes in animal research practices: mapping researchers' attitudes towards animal-free innovations using the Netherlands as an example.

Not available

S-EPMC6477718 | biostudies-literature

Animal product-free formation and cultivation of three-dimensional primary hepatocyte spheroids.

Not available

S-EPMC12799525 | biostudies-literature

An animal-free medium enhances Lactobacillus johnsonii LJO02 supernatant selective efficacy against the methicillin (oxacillin)-resistant Staphylococcus aureus virulence through key-metabolites

The spread of multidrug-resistant (MDR) bacteria, such as the skin commensal Staphylococcus aureus, is a worldwide heath challenge; therefore, new methods to counteract the over-colonization and virulence of opportunistic pathogenic biotypes are highly urgent. We characterized and compared the acti...

ORGANISM(S): Lactobacillus johnsonii Lacticaseibacillus rhamnosus

2022-06-09 | PXD030916 | Pride

Lacticaseibacillus rhamnosus Scfas Cell-free supernatants Lactobacillus johnsonii Proteimics Staphylococcus aureus

Young TPI: empowering animal-free science among the next- generation of scientists.

Not available

S-EPMC11776087 | biostudies-literature

Integrated Multi-Omic Characterization of the Detachment Process of Adherent Vero Cells with Animal-Based and Animal-Origin-Free Enzymes.

Not available

S-EPMC9656133 | biostudies-literature

Development of an Extracorporeal Perfusion Device for Small Animal Free Flaps.

Not available

S-EPMC4726627 | biostudies-literature

Serum-free alginate-C2C12 cells microcapsule as a model of alternative animal protein source

Not available

S-EPMC10213942 | biostudies-literature

Animal-free safety assessment of chemicals: an innovation system perspective.

Not available

S-EPMC11742464 | biostudies-literature

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