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ProteomicsMechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis
In animals, mitosis involves the breakdown of the nucleus. The reassembly of a nucleus after mitosis requires the reformation of the nuclear envelope around a single mass of chromosomes. This process requires Ankle2 (also known as LEM4 in humans) which interacts with PP2A and promotes the function o...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-01-31 | PXD059738 | Pride
Mitosis Nuclear envelope Pp2a Baf Ankle2 Lamin Nucleus Drosophila 
UnknownMicrocephaly protein ANKLE2 promotes Zika virus replication.
Not available
S-EPMC11796389 | biostudies-literature
UnknownMechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis.
Not available
S-EPMC11835388 | biostudies-literature
UnknownANKLE2-related microcephaly: A variable microcephaly syndrome resembling Zika infection.
Not available
S-EPMC9380164 | biostudies-literature
UnknownMutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly.
Not available
S-EPMC6917859 | biostudies-literature
GenomicsGenome-wide profiling of Zfp335 binding sites in thymocytes
The generation of naM-CM-/ve T lymphocytes is critical for immune function yet the mechanisms governing their maturation remain incompletely understood. We have identified a mouse mutant, bloto, that harbors a hypomorphic mutation in the zinc finger protein Zfp335. Mutant blt/blt mice exhibit a naM-...
ORGANISM(S): Mus musculus 
2014-10-17 | E-GEOD-58333 | biostudies-arrayexpress
UnknownComparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis.
Not available
S-EPMC6474419 | biostudies-literature
UnknownNuclear reassembly defects after mitosis trigger apoptotic and p53-dependent safeguard mechanisms in Drosophila.
Not available
S-EPMC11379398 | biostudies-literature
GenomicsGenome-wide profiling of Zfp335 binding sites in thymocytes
The generation of naïve T lymphocytes is critical for immune function yet the mechanisms governing their maturation remain incompletely understood. We have identified a mouse mutant, bloto, that harbors a hypomorphic mutation in the zinc finger protein Zfp335. Mutant blt/blt mice exhibit a naïve T c...
ORGANISM(S): Mus musculus 
2014-10-17 | GSE58333 | GEO
TranscriptomicsGene expression profiling of recent thymic emigrants (RTEs) from a mouse strain with an ENU-induced mutation in Zfp335
The generation of naïve T lymphocytes is critical for immune function yet the mechanisms governing their maturation remain incompletely understood. We have identified a mouse mutant, bloto, that harbors a hypomorphic mutation in the zinc finger protein Zfp335. Mutant blt/blt mice exhibit a naïve T c...
ORGANISM(S): Mus musculus 
2014-10-17 | GSE58289 | GEO
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