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TranscriptomicsStochastic genome-nuclear lamina interactions: Modulating roles of Lamin A and BAF
The nuclear lamina (NL) is a filamentous layer lining the inner-nuclear-membrane (INM) that aids in the organization of the genome in large domains of low transcriptional activity. Recently, it was shown that the single-cell genome-NL interactions are much more dynamic than previously anticipated, w...
ORGANISM(S): Homo sapiens 
2014-02-15 | E-GEOD-55066 | biostudies-arrayexpress
MetabolomicsBAF60a LKO Liver specific knockout Bile acid
Not available
ORGANISM(S): Mus musculus 
ST000193 | MetabolomicsWorkbench
ModelsPMCA knowledge page
Exposure with the id: baf
baf | Physiome Model Repository
TranscriptomicsTranscription profiling of mouse hematopoietic Baf-3 cells inducibly expressing transcription factor Sp1
Inducible expression of transcription factor Sp1 in hematopoietic baf-3 cells
ORGANISM(S): Mus musculus 
2009-02-10 | E-MEXP-1702 | biostudies-arrayexpress
ProteomicsSynaptic Activity Causes Minute-scale Changes in BAF Complex Composition and Function
Genes encoding subunits of the SWI/SNF or BAF ATP-dependent chromatin remodeling complex are among the most enriched for deleterious de novo mutations in intellectual disabilities and autism spectrum disorder, but the causative molecular pathways are not fully known1,2. Synaptic activity in neurons ...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-28 | PXD046031 | Pride
Baf200/arid2 Chromatin remodeling Swi/snf Baf 
MetabolomicsMetabolomics of human primary B-ALL cells treated by BCR-Abl1 inhibitor, STI571, and p190 BCR-Abl+ BAF3 cells with ASS1 knockdown
Analyze the Metabolomics changes in B-ALL cells after the treatment of imatinib and p190+ BAF3 cells with ASS1 knockdown or left untreated. two methods as the below LC-MS description showed were used.
2026-07-08 | MTBLS14638 | MetaboLights
ProteomicsA structural model of the human mSWI/SNF (BAF) complex bound to the nucleosome informs disease mechanisms
Mammalian SWI/SNF complexes are multi-component ATP-dependent chromatin-remodeling complexes that regulate genomic architecture. Here we present the first structural model of the human canonical BAF chromatin-remodeling complex bound to a nucleosome generated using cryo-EM, cross-linking mass spectr...
ORGANISM(S): Homo sapiens (Human) 
2021-02-10 | PXD020992 | Pride
Homology model Cryo-em Atp-dependent chromatin remodeling Nucleosome acidic patch Yeast swi/snf Mammalian swi/snf Canonical baf complex Human disease Mutations 
ProteomicsAcute BAF perturbation causes immediate changes in chromatin accessibility
Loss-of-function mutations in genes coding for subunits of the large, multifarious BRG1/BRM associated factor (BAF) chromatin remodeling complexes are frequently causative for cancer or developmental diseases1-5. Cells lacking the most frequently mutated subunits like the ATPase SMARCA4 typically ex...
ORGANISM(S): Homo sapiens (Human) 
2020-12-23 | PXD018381 | Pride
Atac-seq Enhancer Dtag knock-in Chromatin remodeling Baf complex Chromatin accessibility Acute chemical degradation Synthetic lethality Mammalian swi/snf complex Kinetics 
ProteomicsMudPIT analyses of the proteins co-purified with components of the LSD1 (KDM1A) transcriptional repressor complex and the non-canonical BAF complex, immuno-precipitated from MKL-1 and WaGa MCC cell lines
Protein Complexes Purification: Immunoprecipitations were performed with antibodies to LSD1 (2139; Cell signaling technology), INSM1 Mouse (SC-271408, Santa Cruz Biotechnology), RCOR2 (23969-1-AP; Proteintech Group), BRD9 (61537; Active Motif Rabbit), and normal Rabbit IgG (2729; Cell signaling tech...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-01-25 | MSV000083364 | MassIVE
GenomicsSS18-SSX-mediated hijacking of BAF complexes drives synovial sarcoma
Synovial sarcoma (SS) is defined by a recurrent t(x;18) chromosomal translocation, which produces the hallmark SS18-SSX oncogenic fusion. Incorporation of SS18-SSX into BAF complexes renders BAF complexes aberrant in two distinct manners: the addition of 78aa of SSX onto SS18, and concomitant loss o...
EGAS00001002920 | EGA
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