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ProteomicsSynaptic Activity Causes Minute-scale Changes in BAF Complex Composition and Function
Genes encoding subunits of the SWI/SNF or BAF ATP-dependent chromatin remodeling complex are among the most enriched for deleterious de novo mutations in intellectual disabilities and autism spectrum disorder, but the causative molecular pathways are not fully known1,2. Synaptic activity in neurons ...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-28 | PXD046031 | Pride
Baf200/arid2 Chromatin remodeling Swi/snf Baf 
TranscriptomicsChIP-chip from Ehrlichia chaffeensis-infected THP-1 cells with ankyrin repeat-containing protein, p200
Host genes interacting with ankyrin repeat-containing protein, p200, in Ehrlichia chaffeensis-infected monocytes. Chromatin immunoprecipitation (ChIP) together with microarray (chip) analysis demonstrated enrichment of relatively small subset (n=456) of host cell genes associated with molecular and ...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-13464 | biostudies-arrayexpress
UnknownBAF200 is required for heart morphogenesis and coronary artery development.
Not available
S-EPMC4192121 | biostudies-literature
TranscriptomicsARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [RNA-seq]
Subunits of SWI/SNF chromatin remodeling complexes are frequently mutated in human malignancies. The PBAF complex is composed of multiple subunits, including the putative tumor suppressor proteins PBRM1 (BAF180) and ARID2 (BAF200) that are unique to this SWI/SNF complex. PBRM1 is mutated in various ...
ORGANISM(S): Homo sapiens 
2018-08-14 | GSE102806 | GEO
GenomicsARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [ATAC-seq]
Subunits of SWI/SNF chromatin remodeling complexes are frequently mutated in human malignancies. The PBAF complex is composed of multiple subunits, including the putative tumor suppressor proteins PBRM1 (BAF180) and ARID2 (BAF200) that are unique to this SWI/SNF complex. PBRM1 is mutated in various ...
ORGANISM(S): Homo sapiens 
2018-08-14 | GSE102805 | GEO
GenomicsARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [ARID2 ChIP-seq]
Subunits of SWI/SNF chromatin remodeling complexes are frequently mutated in human malignancies. The PBAF complex is composed of multiple subunits, including the putative tumor suppressor proteins PBRM1 (BAF180) and ARID2 (BAF200) that are unique to this SWI/SNF complex. PBRM1 is mutated in various ...
ORGANISM(S): Homo sapiens 
2018-08-14 | GSE102803 | GEO
GenomicsARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [Histone modification native ChIP-seq]
Subunits of SWI/SNF chromatin remodeling complexes are frequently mutated in human malignancies. The PBAF complex is composed of multiple subunits, including the putative tumor suppressor proteins PBRM1 (BAF180) and ARID2 (BAF200) that are unique to this SWI/SNF complex. PBRM1 is mutated in various ...
ORGANISM(S): Homo sapiens 
2018-08-14 | GSE102804 | GEO
TranscriptomicsARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [microarray]
Subunits of SWI/SNF chromatin remodeling complexes are frequently mutated in human malignancies. The PBAF complex is composed of multiple subunits, including the putative tumor suppressor proteins PBRM1 (BAF180) and ARID2 (BAF200) that are unique to this SWI/SNF complex. PBRM1 is mutated in various ...
ORGANISM(S): Mus musculus 
2018-08-14 | GSE102656 | GEO
UnknownThe chromatin-remodeling subunit Baf200 promotes homology-directed DNA repair and regulates distinct chromatin-remodeling complexes.
Not available
S-EPMC5437250 | biostudies-literature
TranscriptomicsThe effects of PBRM1 loss on the ccRCC transcriptome
Subunits of SWI/SNF chromatin remodeling complexes are frequently mutated in human malignancies. The PBAF complex is composed of multiple subunits, including the tumor suppressor protein PBRM1 (BAF180), as well as ARID2 (BAF200), that are unique to this SWI/SNF complex. PBRM1 is mutated in various c...
ORGANISM(S): Homo sapiens 
2022-02-07 | GSE196129 | GEO
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