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TranscriptomicsInvestigation of over-expressing Annexin receptor cell line with and without agonists
The therapeutic potential of pro-resolution factors in determining the outcome of inflammatory events has gained ground over the past decade. However, the attention has been focused on the non-genomic effects of these endogenous, anti-inflammatory substances. In this study, we have focused our atten...
ORGANISM(S): Homo sapiens 
2010-09-28 | E-GEOD-14807 | biostudies-arrayexpress
TranscriptomicsAnnexin A2 controls pancreatic cancer invasion and metastasis through a novel axon guidance pathway
The mechanisms involved in promoting metastasis of pancreatic ductal adenocarcinoma have yet to be elucidated. Here, we show that AnnexinA2 regulates the secretion of Semaphorin3D from pancreatic tumor cells allowing it to bind to its receptor PlexinD1 on the surface of the tumor cell, which induces...
ORGANISM(S): Mus musculus 
2015-09-03 | E-GEOD-62285 | biostudies-arrayexpress
TranscriptomicsAnnexin A2 Modulates Radiation-Sensitive Transcriptional Programming and Cell Fate
Whole genome expression profiling in the presence and absence of annexin A2 [shRNA] identified fundamentally altered transcriptional programming that changes the radioresponsive transcriptome. Bioinformatics predicted that silencing AnxA2 may enhance cell death responses to stress in association wit...
ORGANISM(S): Mus musculus 
2012-11-28 | E-GEOD-42547 | biostudies-arrayexpress
ProteomicsAnnexin A2 causes motor incoordination via muscle-cerebellum axis in sarcopenia
Annexin A2 causes motor incoordination via muscle-cerebellum axis in sarcopenia
ORGANISM(S): Mus Musculus 
2025-09-22 | PXD068704 |
ProteomicsBinding partners of Annexin A2 in MDA-MB-231 cells
A mass-spec of proteins found bound to Annexin A2 following a immunoprecipitation of Annexin A2 from cell lysate of MDAMB231 cells plated 1) on plastic or 2) on collagen-1
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-11 | MSV000093084 | MassIVE
ProteomicsPathogenic Natural Antibodies Recognizing Annexin IV Are Required to Develop Intestinal Ischemia-Reperfusion Injury
Intestinal ischemia-reperfusion (IR) injury is initiated when natural IgM antibodies recognize neo-epitopes that are revealed on ischemic cells. The target molecules and mechanisms whereby these neo-epitopes become accessible to recognition are not well understood. Proposing that isolated intestinal...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-14862 | biostudies-arrayexpress
TranscriptomicsAnnexin A2 Modulates Radiation-Sensitive Transcriptional Programming and Cell Fate
Whole genome expression profiling in the presence and absence of annexin A2 [shRNA] identified fundamentally altered transcriptional programming that changes the radioresponsive transcriptome. Bioinformatics predicted that silencing AnxA2 may enhance cell death responses to stress in association wit...
ORGANISM(S): Mus musculus 
2012-11-28 | GSE42547 | GEO
ProteomicsQuantitative proteomic screen identifies Annexin A2 as a host target for Salmonella pathogenicity island-2 effectors SopD2 and PipB2
In this work we use stable isotope labeling of amino acids in cell culture (SILAC) and a S. Typhimurium mutant that secretes increased amounts of effectors to identify cognate effector binding partners during infection. Using this method, we identified the host protein annexin A2 as a binding partne...
ORGANISM(S): Homo sapiens (Human) Salmonella enterica subsp. enterica serovar Typhimurium str. 5579 Salmonella enterica subsp. enterica serovar Typhimurium str. A130 
2022-02-17 | PXD025582 | Pride
Proteomics Silac Salmonella 
TranscriptomicsRole of annexin A2 in muscle repair
Repair of injured muscle involves repair of injured myofibers through the involvement of dysferlin and its interacting partners, including annexin. Studies with mice and patients have established that dysferlin deficit leads to chronic inflammation and adipogenic replacement of the diseased muscle. ...
ORGANISM(S): Mus musculus 
2016-10-04 | GSE87557 | GEO
UnknownGenotoxic agents promote the nuclear accumulation of annexin A2: role of annexin A2 in mitigating DNA damage.
Not available
S-EPMC3511559 | biostudies-literature
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