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Annexin A2 causes motor incoordination via muscle-cerebellum axis in sarcopenia

ABSTRACT: Annexin A2 causes motor incoordination via muscle-cerebellum axis in sarcopenia

ORGANISM(S): Mus Musculus

SUBMITTER: Dongyun Gu

PROVIDER: PXD068704 | iProX | Mon Sep 22 00:00:00 GMT+01:00 2025

REPOSITORIES: iProX

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Annexin A2 Causes Motor Incoordination via Muscle-Cerebellum Axis in Sarcopenia.

Jiao Xin X Wang Zengguang Z Chang Hanwen H Li Yongjin Y Wang Binbin B Shao Xinfa X Zhang Yuxin Y Lin Yixuan Y Jia Xinlin X Zhou Xianhao X Li Wentao W Luo Dinghao D Deng Tanjun T Lin Xingzuan X Xu Chen C Gan Yaokai Y Gu Dongyun D

Journal of cachexia, sarcopenia and muscle 20260201 1

<h4>Background</h4>Sarcopenia is a prevalent age-related disorder characterized by progressive muscle atrophy. Impaired balance is one of its most critical clinical consequences, often leading to falling and even bone fractures. As the cerebellum plays a central role in regulating motor coordination, elucidating the molecular mechanisms underlying imbalance in sarcopenia, particularly those mediated by the muscle-cerebellum axis, remains an important yet unresolved question.<h4>Methods</h4>4D la ...[more]

PMID: 41588637

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