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ProteomicsIntegrated analysis of the anoikis-related signature identifies RAC3 as a novel therapeutic target in hepatocellular carcinoma
Introduction: Anoikis is a form of programmed cell death. Anoikis resistance in hepatocellular carcinoma (HCC) promotes cancer cells shedding from the primary tumor site, thus contributing to survival and distant metastasis. However, the prognostic significance of anoikis-related genes (ARGs) and th...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD057450 | Pride
Rac3 Hcc Anoikis 
GenomicsAdaptive anoikis resistance promotes ovarian cancer metastasis
Adaptive anoikis resistance promotes ovarian cancer metastasis
PRJNA1008671 | ENA
GenomicsBRN2 expression increases anoikis resistance in melanoma.
BRN2 expression increases anoikis resistance in melanoma.
PRJNA608296 | ENA
TranscriptomicsAdaptive anoikis resistance promotes ovarian cancer metastasis
Anoikis resistance or evasion of cell death triggered by cell detachment is a hallmark of cancer that is concurrent with cell survival and metastasis. Phenotypes of anoikis resistant cancer cells have been extensively investigated, however, how exposure to suspension stress may lead to acquisition o...
ORGANISM(S): Homo sapiens 
2024-12-01 | GSE241546 | GEO
GenomicsSPIB promotes anoikis resistance via elevated autolysosomal process in lung cancer cells [ChIP-seq]
SPIB promotes anoikis resistance via elevated autolysosomal process in lung cancer cells [ChIP-seq]
PRJNA516820 | ENA
GenomicsSPIB promotes anoikis resistance via elevated autolysosomal process in lung cancer cells [RNA-seq]
SPIB promotes anoikis resistance via elevated autolysosomal process in lung cancer cells [RNA-seq]
PRJNA417308 | ENA
GenomicsEffect of CDK8/19 kinase inhibitor SNX 631 on OV90 parental and anoikis resistant isogenic lines
Effect of CDK8/19 kinase inhibitor SNX 631 on OV90 parental and anoikis resistant isogenic lines
PRJNA1333704 | ENA
TranscriptomicsGene expression signatures in anoikis-resistance of human prostate PC-3 cells
To investigate potential molecular targets that regulate metastasis and metabolism in anoikis-resistance of prostate cancer cells, we have establised anoikis-resistant prostate PC-3 cells with ultra-low attachment 6-well plates (Corning) and employed whole genome microarray expression profiling as a...
ORGANISM(S): Homo sapiens 
2020-06-26 | GSE100629 | GEO
TranscriptomicsEffect of CDK8/19 kinase inhibitor SNX 631 on OV90 parental and anoikis resistant isogenic lines
Anoikis resistance or evasion of cell death triggered by matrix detachment is a hallmark of cancer cell survival and metastasis. We show that repeated exposure to suspension stress followed by recovery under attached conditions leads to development of anoikis resistance. The acquisition of anoikis r...
ORGANISM(S): Homo sapiens 
2025-12-15 | GSE309005 | GEO
GenomicsYEATS2 Promotes DNA Repair and Induces Anoikis Resistance by Enhancing Chromatin Accessibility to Drive Prostate Cancer Metastasis
YEATS2 Promotes DNA Repair and Induces Anoikis Resistance by Enhancing Chromatin Accessibility to Drive Prostate Cancer Metastasis
PRJEB102114 | ENA
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