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ProteomicsGlaucoma-Associated CDR1 Peptide Promotes RGC Survival in Retinal Explants through Molecular Interaction with Acidic Leucine Rich Nuclear Phosphoprotein 32A (ANP32A)
Glaucoma is a complex, multifactorial optic neuropathy mainly characterized by the progressive loss of retinal ganglion cells (RGCs) and their axons, resulting in a decline of visual function. The pathogenic molecular mechanism of glaucoma is still not well understood, and therapeutic strategies spe...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2023-08-01 | PXD038373 | Pride
Glaucoma Neuroprotection Mass spectrometry Proteomics Anp32a 
GenomicsGene Editing of Anp32a Confers Resistance to Avian Influenza in Chicken
Gene Editing of Anp32a Confers Resistance to Avian Influenza in Chicken
PRJNA756092 | ENA
TranscriptomicsComparative analysis of cartilage tissue from ANP32A knockout mice and wildtype C57/Bl6 mice
A genetic association between the ANP32A gene and osteoarthritis has been suggested. We compared transcriptome profiles of the articular cartilage and subchondral bone from mice deficient in ANP32A with wild-type mice to get insights into the role of ANP32A in the pathogenesis of ostearthritis.
ORGANISM(S): Mus musculus 
2018-06-07 | GSE108036 | GEO
GenomicsComparative analysis of cartilage tissue from ANP32A knockout mice and wildtype C57/Bl6 mice
Comparative analysis of cartilage tissue from ANP32A knockout mice and wildtype C57/Bl6 mice
PRJNA422267 | ENA
TranscriptomicsGene Editing of Anp32a Confers Resistance to Avian Influenza in Chicken
Comparison of transcriptomic profiles of primordial germ cells and derived fibroblast cell lines from homozygous, CRISPR/Cas9 gene-edited, ANP32A knockout and mutant chickens
ORGANISM(S): Gallus gallus 
2023-08-15 | GSE182397 | GEO
UnknownMicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4.
Not available
S-EPMC3134876 | biostudies-literature
ProteomicsProteomic analyses identify ANP32A and CAND1 as androgen receptor and splice variant coactivators, whose interactions are regulated by DNA-dependent protein kinase
ARv7, the most prevalent androgen receptor (AR) variant in castration resistant prostate cancer (CRPC), lacks the AR ligand binding domain (LBD) making it resistant to LBD-targeting pharmacological inhibitors, such as enzalutamide. Identifying new prostate cancer therapeutic targets by defining key ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD021462 | Pride
Prostate cancer Coregulators And cand1 Dna-dependent protein kinase Androgen receptor Androgen receptor splice variant Anp32a 
UnknownSpecies difference in ANP32A underlies influenza A virus polymerase host restriction.
Not available
S-EPMC4710677 | biostudies-literature
UnknownSwine ANP32A Supports Avian Influenza Virus Polymerase.
Not available
S-EPMC7307101 | biostudies-literature
UnknownSmall peptide targeting ANP32A as a novel strategy for acute myeloid leukemia therapy.
Not available
S-EPMC8529559 | biostudies-literature
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