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UnknownRandomized, phase III trial of first-line figitumumab in combination with paclitaxel and carboplatin versus paclitaxel and carboplatin alone in patients with advanced non-small-cell lung cancer.
Not available
S-EPMC4067944 | biostudies-literature
UnknownCognitive behavioral therapy in depressed cardiac surgery patients: role of ejection fraction.
Not available
S-EPMC4207721 | biostudies-literature
GenomicsCIDR: Collaborative Study on the Genetics of Alcoholism Case Control Study

This is a case-control study of alcoholism, in which the subjects have been drawn from the Collaborative Study on the Genetics of Alcoholism (COGA), a large, ongoing family-based study that includes subjects from seven sites around the US. COGA has gathered detailed, standardized data on ...

phs000125.v1.p1 | EGA
TranscriptomicsGene Expression Changes Associated With TLR2 Mediated Inhibition of Allergen Specific TH2 Response In Vitro
Investigation of the gene expression changes associated with TLR2 adjuvant (lipoteichoic acid; LTA) inhibition of allergic TH2 responses in peripheral blood mononuclear cell cultures (derived from house dust mite allergic individuals) stimulated with house dust mite extract. Pooled samples from 5 in...
ORGANISM(S): Homo sapiens 
2012-07-18 | E-GEOD-39476 | biostudies-arrayexpress
ProteomicsDataset for 3,3'-Dichlorobiphenyl (PCB 11) Alters the Hepatic Expression of Cytochrome P450 Enzymes in the Liver of Mouse Dams Exposed Orally During Pregnancy and Lactation
As part of a larger study on neurodevelopmental effects of lower chlorinated PCB 11, we characterized PCB 11 distribution in postweaning mouse dams orally developmentally exposed to PCB 11 via the diet. We used and liquid chromatography tandem mass spectrometry (LC MS/MS) based proteomics to map cha...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-11-10 | MSV000099827 | MassIVE
GenomicsCytokine-mediated differentiation reflects genome-wide loss of a uSTAT transcriptional program
uSTAT transcriptional program HPC7 cells were fixed with either 1% formaldehyde for 10 mins. Chromatin was isolated, sonicated for 7 mins (30 sec on, 30 sec off), and specific antibodies were used to pull down the transcription factors of insterest after a pre-clearing step. Chromatin was washed, de...
ORGANISM(S): Mus musculus 
2016-01-05 | E-GEOD-70697 | biostudies-arrayexpress
GenomicsStudy of Addiction: Genetics and Environment (SAGE)

This study is part of the Gene Environment Association Studies initiative (GENEVA) funded by the National Human Genome Research Institute. The overarching goal is to identify novel genetic factors that contribute to addiction through a large-scale genome-wide association study of DSM-IV alcoh...

phs000092.v1.p1 | EGA
TranscriptomicsDeciphering the molecular immune response to COVID-19 using single cell multi-omics
Multi-omics single-cell profiling of surface proteins, gene expression and lymphocyte immune receptors from hospitalised COVID-19 patient peripheral blood immune cells and healthy controls donors. Identification of the coordinated immune cell compositional and state changes in response to SARS-CoV-2...
ORGANISM(S): Homo sapiens 
2021-03-17 | E-MTAB-10026 | biostudies-arrayexpress
TranscriptomicsCandidate driver genes in Sѐzary syndrome
Illumina human Omni5Exome arrays were used to investigate CNVs in Sѐzary syndrome tumours as part of a larger study involving whole exome sequencing of the same samples and targeted resequencing of a further cohort. 16 Samples underwent SNP array including 10 tumour/gDNA matched samples that also u...
ORGANISM(S): Homo sapiens 
2016-07-22 | E-GEOD-80650 | biostudies-arrayexpress
TranscriptomicsThe TMAO Generating Enzyme Flavin Monooxygenase 3 is a Central Regulator of Cholesterol Balance
Circulating levels of the gut microbe-derived metabolite trimethylamine-N-oxide(TMAO) have recently been linked to cardiovascular disease (CVD) risk. Here we performed transcriptional profiling in mouse models of altered reverse cholesterol transport (RCT), and serendipitously identified the TMAO-ge...
ORGANISM(S): Mus musculus 
2014-12-19 | E-GEOD-64326 | biostudies-arrayexpress
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