Anti-tumor response

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gut metagenome (2)
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Mus (1)
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Reference (1)
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Technology Type

Mass Spectrometry (125)
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Mass spectrometry assay (27)
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Fluorescence intensity (6)
Illumina HiSeq 2500, ILLUMINA (5)
Fluorescence imaging (5)
RPPA (4)
Gel-based experiment (4)
SWATH MS (4)
ILLUMINA, Illumina HiSeq 2500 (2)
NMR spectroscopy (2)
Illumina HiSeq 4000, ILLUMINA (1)
IlluminaHuman HT12, IlluminaHuman AWG-6 and HT12 (1)
Illumina (1)
Illumina HiSeq 2000 (1)
Illumina MiSeq (1)
NMR spectroscopy assay (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
HDMSE (1)
Immunopeptidomics (1)
Proteogenomics (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (32)
Illumina HiSeq 2500 (13)
Illumina HiSeq 4000 (13)
NextSeq 500 (12)
Illumina HiSeq 2000 (7)
Illumina MiSeq (6)
Illumina NovaSeq X (4)
DNBSEQ-T7 (4)
NextSeq 2000 (3)
Gene Titan (2)
BAS-5000 [FUJIFILM] (2)
NextSeq 550 (2)
Illumina HiSeq 2000 platform (1)
10X Genomics Single Cell, V3.1 (1)
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SPF Animal Room (1)
PCR Thermocycler, Fragment Analyzer (1)
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Biosafety Cabinet, Liquid Nitrogen Tank, -80°C Freezer (1)
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MiRNeasy Micro kit (1)
Radial JawTM (1)
Qubit 4.0 and TapeStation (1)
Element AVITI (1)
Solexa 2G Genome Analyzer (1)
BD FACSAria III (1)
Not applicable (1)
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BD Influx (1)

Publication Date

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2015 (423)
2010 (354)
2013 (337)
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2014 (301)
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2012 (295)
2011 (251)
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2016 (174)
2008 (161)
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2021 (137)
2009 (115)
2020 (111)
2007 (87)
2018 (68)
2019 (63)
2017 (53)
2006 (16)
2005 (13)
2004 (2)
2003 (2)
2002 (1)

UNIPROT ID/AC

Q9NZS9 (1)
P21580 (1)
Q12933 (1)
Q15628 (1)
Q13546 (1)
P19438 (1)
P01375 (1)
O15111 (1)
P25963 (1)
Q13158 (1)
P25445 (1)
P48023 (1)
P08887 (1)
P98170 (1)
P55212 (1)
P42574 (1)
Q14790 (1)
O15519 (1)
P19838 (1)
P05231 (1)
P01137 (1)
P09874 (1)
6PGL_HELPY (1)
85962.C694_00040 (1)
85962.C694_00275 (1)
85962.C694_00510 (1)
85962.C694_00935 (1)
85962.C694_01080 (1)
85962.C694_01205 (1)
85962.C694_02750 (1)

ENSEMBL ID

ENST00000309955 (1)
ENST00000371199 (1)
ENST00000216797 (1)
ENST00000237289 (1)

CHEBI ID

CHEBI:16708 (13)
CHEBI:17368 (12)
CHEBI:28044 (11)
CHEBI:17596 (11)
CHEBI:16335 (10)
CHEBI:15891 (10)
CHEBI:16704 (10)
CHEBI:18012 (10)
CHEBI:16737 (10)
CHEBI:17822 (9)
CHEBI:16856 (9)
CHEBI:17568 (9)
CHEBI:27897 (9)
CHEBI:18237 (8)
CHEBI:15741 (8)
CHEBI:6650 (8)
CHEBI:17154 (8)
CHEBI:16865 (8)
CHEBI:16566 (8)
CHEBI:16235 (8)
CHEBI:7916 (8)
CHEBI:17750 (8)
CHEBI:29016 (8)
CHEBI:17351 (8)
CHEBI:30769 (8)
CHEBI:17172 (7)
CHEBI:16450 (7)
CHEBI:17858 (7)
CHEBI:27570 (7)
CHEBI:17089 (1)

Metabolite Name

Creatine (16)
Hypoxanthine (16)
Adenine (15)
Choline (14)
Taurine (14)
Adenosine (14)
Uridine (14)
Creatinine (14)
Xanthine (13)
L-Phenylalanine (13)
Uracil (12)
L-Histidine (12)
N-Acetyl-L-alanine (12)
Inosine (12)
Betaine (11)
Guanine (11)
L-Tyrosine (11)
Succinic acid (10)
Indole (10)
Citric acid (10)
L-Glutamine (10)
Uric acid (10)
Cytidine (10)
Guanosine (10)
Thymidine (10)
Corticosterone (9)
Thymine (9)
Pyroglutamic acid (9)
L-Proline (9)
L-Arginine (9)

First Public Date

2025 (441)
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2020 (107)
2014 (91)
2019 (70)
2017 (52)
2018 (41)
2015 (39)
2016 (26)
2013 (8)

Modelling Approach

Ordinary differential equation model (12)
Computational model (2)
Boolean model (1)

Study status

Completed (19)
Recruiting (10)
Not provided (7)
Terminated (6)
Withdrawn (5)
Not yet recruiting (4)
Ongoing (1)
Active, not recruiting (1)

Lab affiliation

Department of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea (2)
Department of Pathology, Dalhousie University (2)
Immunology Unit, Department of Cell Biology, Physiology and Immunology, Institut de Biotecnologia i Biomedicina (IBB), Universitat Autònoma de Barcelona (UAB), Bellaterra (Cerdanyola del Vallès), Spain Biosensing and Bioanalysis Group, Institut de Biotecnologia i Biomedicina (IBB), Universitat Autònoma de Barcelona (UAB), Bellaterra (Cerdanyola del Vallès), Spain (2)
Moffitt Cancer Center Tampa, FL, USA (2)
Qilu Hospital of Shandong University (2)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (2)
Université libre de Buxelles (ULB), Laboratory of Stem Cells and Cancer, 808 route de Lennik, 1070 Brussels, Belgium ; WELBIO, Université Libre de Bruxelles (ULB), 1070 Bruxelles, Belgium (2)
Virginia Tech (2)
All liquid chromatography MS/MS (LC-MS/MS) data were searched against the relevant database using PEAKS 10.5 or Peaks X Pro (Bioinformatics Solution Inc.). For peptide identification, tolerance was set at 10 ppm and 0.01 Da for precursor and fragment ions, respectively. The occurrences of oxidation (M), deamidation and TMT modification were set as variable modifications (1)
Assistant Professor of Medicine Department of Medicine Tulane University School of Medicine 1430 Tulane Avenue, New Orleans, LA,70114 (1)
Bioheat and mass transfer laboratory, Med-X Research Institute, Shanghai Jiao Tong University (1)
Biological Mass Spectrometry Lab, Department of Translational Medicine (DiMeT),Center for Translational Research on Autoimmune & Allergic Diseases - CAAD, University of Piemonte Orientale Corso Trieste 15/A, 28100, Novara, Italy. (1)
BriaCell Therapeutics Corporation, Berkeley, CA, USA (1)
CNIO (1)
CRG, UPF (1)
CRUK - Beatson Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (1)
Cambridge University (1)
Cancer Biology Department, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. (1)
Cancer Program, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia (1)
Chan Zuckerberg Biohub, Stanford, CA, USA (1)
Charité-University Medicine Berlin (1)
Core Unit Proteomics, Berlin Institute of Health at Charité-Universitätsmedizin Berlin and Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany (1)
Core facilities National Institute of Health Viale Regina Elena 299 00161 Rome Italy (1)
Department of Biochemistry & Biotechnology, University of Thessaly, Biopolis, 41500, Larissa, Greece (1)
Department of Biochemistry and Molecular Biology Hollings Cancer Center Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC 29425; (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Biochemistry, School of Medicine, Case Western Reserve University (1)
Department of Biological Engineering, Massachusetts Institute of Technology (1)
Department of Biology, Technion - Israel Institute of Technology, Haifa, Israel (1)
Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA (1)

Keyword

Bevacizumab (5)
Cetuximab (5)
Irinotecan (4)
Oxaliplatin (4)
Pembrolizumab (3)
Capecitabine (3)
Immunotherapy (3)
Leucovorin (3)
T cell (2)
Vaccines (2)
Safety (2)
Cryoablation (2)
AlloStim (2)
Atezolizumab (2)
Radiation (2)
Durvalumab (2)
Celecoxib (2)
Antibodies (2)
Fluorouracil (2)
Gastric (gastroesophageal cancer) (1)
CD39 (1)
Adenosine Pathway (1)
Immunotherapy Immuno-oncology (1)
Budigalimab (1)
TTX-030 (1)
Urothelial cell cancer (1)
Régorafenib (1)
Cyclophosphamide métronomique (1)
Capécitabine (1)
Aspirine (1)

IsPrivate

False (18)

Submitter Keywords

Immuno-oncology (8)
FAIR-AIML (2)
Machine Learning Model (2)

Modification

Not available (1)

Study type

Transcription profiling by array (1885)
RNA-seq of coding RNA (266)
Unknown experiment type (75)
ChIP-seq (45)
Proteomic profiling by array (28)
RNA-seq of non coding RNA (28)
Comparative genomic hybridization by array (24)
RNA-seq of coding RNA from single cells (23)
ChIP-chip by tiling array (20)
Other (15)
Methylation profiling by array (13)
Transcription profiling by SAGE (11)
Transcription profiling by RT-PCR (11)
Transcription profiling by tiling array (8)
Genotyping by array (7)
RNA-seq of total RNA (7)
DNA-seq (5)
Methylation profiling by high throughput sequencing (4)
Cell line - One-color microarray (3)
Animal - High-throughput sequencing (3)
MicroRNA profiling by array (3)
Human - High-throughput sequencing (2)
RNAi profiling by array (2)
ChIP-chip by array (2)
MicroRNA profiling by high throughput sequencing (2)
ChIP-chip by SNP array (1)
RNA-seq of non coding RNA from single cells (1)
Animal - One-color microarray (1)
Human - Single-cell sequencing (1)
High-throughput sequencing (1)

Release Date

2022 (1519)
2023 (1402)
2021 (1285)
2025 (1241)
2024 (1198)
2020 (987)
2019 (741)
2015 (699)
2018 (550)
2016 (523)
2014 (519)
2017 (479)
2013 (472)
2010 (431)
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2011 (341)
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2007 (99)
2006 (26)
2005 (18)
2004 (8)
2003 (3)
1998 (3)
2002 (2)
2001 (1)
2000 (1)
1999 (1)
1997 (1)

Location

United States (13)
France (10)
China (5)
Taiwan (4)
Italy (4)
Netherlands (4)
Spain (3)
Belgium (3)
Saudi Arabia (2)
Denmark (2)
Turkey (2)
South Korea (2)
Germany (2)
Ireland (1)
Thailand (1)
Singapore (1)
New Zealand (1)
Mexico (1)
Colombia (1)
Russia (1)
Poland (1)
Israel (1)
Argentina (1)
Canada (1)
Australia (1)
United Kingdom (1)

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Low-Protein Diet Enhances Anti-Tumor Immunity in Pancreatic Cancer through Microbiota-Derived Uridine Diphosphate-Galactose

Low-protein diets (LPD) have been linked to improved metabolic health, but their role in pancreatic ductal adenocarcinoma (PDAC) immunotherapy remains unclear. Here we show that an LPD suppresses PDAC progression in male mice by remodeling the gut microbiota and activating anti-tumor immunity. LPD p...

2026-07-09 | MTBLS14989 | MetaboLights

Pharmacological Targeting of ALDH1a2 in Dendritic Cells Enhances Antigen Presentation, T Cell Activation and Anti-tumor immunity

Dendritic cell (DC) vaccines have been proposed as cancer immunotherapies due to their role as crucial antigen-presenting cells that regulate T cell functions. Despite considerable efforts to optimize ex vivo priming of DCs, DC vaccines have rarely been successful, suggesting the presence of unknown...

2025-11-03 | MTBLS10389 | MetaboLights

Boer1985 - Macrophage T cell interaction in anti-tumor response

In this paper we present a model of the macrophage T lymphocyte interactions that generate an anti-tumor immune response. The modseple cifies i) induction of cytotoxic T lymphocytes, ii) antigen presentation by macrophages, which leads to iii) activation of helper T cells, and iv) production of lymp...

2019-11-13 | MODEL1911130003 | BioModels

Immuno-oncology

Circulating cell populations as response predictors and targets to improve immunotherapy in metastatic lung cancer

The effectiveness of immunotherapy varies among patients with advanced non-small cell lung cancer (NSCLC). Here we investigated the baseline immune status in stage IV NSCLC patients treated with anti-PD-1 plus chemotherapy to understand the immune mechanisms and unveil systemic markers associated...

2025-10-16 | MTBLS13150 | MetaboLights

Interleukin-6 induced ‘acute’ response promotes Th1 anti-tumor immunity in cryo-thermal therapy: shotgun proteomics

Cryo-thermal therapy has been proven to be a promising novel systemic strategy for advanced breast cancer, resulting in higher incidence of tumor regression and enhanced remission of metastasis. The mechanism by which such strategy boosts the anti-tumor activity remains unclear. To gain a system-wid...

ORGANISM(S): Mus musculus (Mouse)

2016-05-12 | PXD003136 | Pride

Acute phase response Th1 anti-tumor immunity Cryo-thermal therapy Interleukin-6 Parallel reaction monitoring

Golgi-ER Axis Regulates Anti-Tumor T Cell Immunotherapeutic Response

PRJNA1048442 | ENA

Inhibition of MAN2A1 enhances tumor response to anti-PD-L1

PRJNA640958 | ENA

Cytoplasmic UHRF1 restrains MHC-I-mediated anti-tumor immune response

PRJNA1085386 | ENA

VISTA immune-checkpoint blunts radiotherapy induced anti-tumor immune response

PRJNA1256782 | ENA

Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy