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GenomicsThe antibiofilm protein alterocin
Alterocin is an antibiofilm protein secreted by Pseudoalteromonas sp. 3J6
PRJEB37533 | ENA
GenomicsFragment-like pyrazole-tetrazoles provide a scaffold for antibiofilm drug discovery
Fragment-like pyrazole-tetrazoles provide a scaffold for antibiofilm drug discovery
PRJNA1532884 | ENA
MetabolomicsDeciphering the Anti-Biofilm Mechanism of Anthraquinone-2-Carboxylic Acid Against MRSA by Comprehensive Multi-Omics Analysis

Background: Methicillin-resistant Staphylococcus aureus (MRSA) biofilms exhibit high levels of drug resistance and cause nosocomial infections in humans, thus posing a sustainable global health threat. This underscores the critical need to develop novel antibiofilm therapeutics with high efficacy...

2025-09-18 | MTBLS13012 | MetaboLights
TranscriptomicsFragment-like pyrazole-tetrazoles provide a scaffold for antibiofilm drug discovery
Antimicrobial drug discovery is at a standstill, with many frontline antimicrobial drug classes identified in the previous century. Many human pathogens are now resistant to many of these classes, straining the healthcare system and putting lives at risk. ESKAPE pathogens are among the most commonly...
ORGANISM(S): Staphylococcus aureus 
2026-10-01 | GSE348130 | GEO
Genomicsn vitro antibiofilm and intracellular activity of delafloxacin against Staphylococcus aureus and Staphylococcus epidermidis in bone and joint infections.
Intracellular and antibiofilm activity of delafloxacin against staphylococci.
PRJEB98851 | ENA
ProteomicsAntibiofilm and antivirulence properties of 6-polyaminosteroid derivatives against antibiotic-resistant bacteria
The emergence of multi-drug resistant pathogens is a major public health problem, leading to rethink and innovate in our bacterial control strategies. Here, we explore the anti-biofilm and anti-virulence activities of nineteen 6-polyaminosterol derivatives (squalamine-based), presenting a modulation...
ORGANISM(S): Pseudomonas aeruginosa PAO1H2O Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377) 
2024-05-22 | PXD047333 | Pride
6-aminosteroid derivatives Antivirulence Pyocyanin Antibiofilm 
ProteomicsA Water-Soluble Aggregation-Induced Emission Photosensitizer with Intrinsic Antibacterial Activity as an Antiplanktonic and Antibiofilm Therapeutic Agent
Photosensitizers (PS)s with aggregation-induced emission (AIE) properties have gained popularity in treating bacterial infections. However, most AIE PSs have poor water solubility and low selectivity, which greatly limit their applications in biological systems. Herein, we report a water-soluble and...
ORGANISM(S): Staphylococcus aureus 
2025-05-07 | PXD060538 | Pride
Lc-ms Biofilm Staphylococcus aureus 
Genomics
Antibiofilm activity of crab antimicrobial protein against Vibrio parahaemolyticus
PRJNA932196 | ENA
MetabolomicsGNPS A07A1 Actinobacteria as Antibiofilm
A07A1 as antibiofilm from marine actinobacteria, isolate actinobacteria was obtain from marine biota
ORGANISM(S): Actinobacteria <class> (ncbitaxon:1760) 
2022-07-05 | MSV000089819 | GNPS
GenomicsAn antibiofilm effect against Salmonella typhimurium rdar biofilm formation upon treatment with the macrolide clarithromycin
An antibiofilm effect against Salmonella typhimurium rdar biofilm formation upon treatment with the macrolide clarithromycin
PRJNA662483 | ENA
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