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OtherAssessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.
Data from ProteomeXchange, PXD ID: PXD002534. File: GR_130129_20_OT3_NT_L3MBTL2_FAB_31_G11_2_HEK293.mzXML. Published as part of Nat Methods. 2015 Jun 29 . From the Abstract: {{i}} ... We describe a mass spectrometry-based standard operating procedure for scoring immunoprecipitation antibody quality...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32320016573 | GPMDB
Resource Reanalysis 
ProteomicsA method to characterize antibody selectivity immunoprecipitation
Antibodies are used in multiple cell biology applications but there are methods to assess antibody quality, riskingdata integrity and repr developed a standard operating procedure using HEK293 cells to score and antibodies for suitability in immunoprecipitation. This method, validated in in fourind...
ORGANISM(S): Homo sapiens (Human) 
2015-07-15 | PXD002412 | Pride
Mass spectrometry Immunoprecipitation Antibody selectivity and specificity 
ProteomicsA method to characterize antibody selectivity immunoprecipitation, part 2
Antibodies are used in multiple cell biology applications but there are methods to assess antibody quality, riskingdata integrity and repr developed a standard operating procedure using HEK293 cells to score and antibodies for suitability in immunoprecipitation. This method, validated in in fourind...
ORGANISM(S): Homo sapiens (Human) 
2015-07-15 | PXD002534 | Pride
Mass spectrometry Immunoprecipitation Antibody selectivity and specificity 
UnknownLong-acting antibody ligand mimetics for HER4-selective agonism.
Not available
S-EPMC7566517 | biostudies-literature
UnknownDevelopment of antibodies against severe fever with thrombocytopenia syndrome virus nucleoprotein for diagnosis.
Not available
S-EPMC12145327 | biostudies-literature
UnknownA novel bispecific antibody drug conjugate targeting HER2 and HER3 with potent therapeutic efficacy against breast cancer.
Not available
S-EPMC11272928 | biostudies-literature
UnknownAb locks for improving the selectivity and safety of antibody drugs.
Not available
S-EPMC7318374 | biostudies-literature
ProteomicsAnalysis of N-Glycosylation for SARS-CoV-2 expressed receptor-binding domain VOCs and membrane protein with LC-MS.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect human cells by first attaching to the ACE-2 receptor via its receptor-binding domain (RBD) in the spike protein. We investigated the influence of N-glycosylation sites of the RBD and the membrane (M) protein on IgG antibody bind...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
PXD048930 | panorama
UnknownReactivity of human AGO2 monoclonal antibody 11A9 with the SWI/SNF complex: A case study for rigorously defining antibody selectivity.
Not available
S-EPMC5544689 | biostudies-literature
UnknownEngineering neprilysin activity and specificity to create a novel therapeutic for Alzheimer's disease.
Not available
S-EPMC4121237 | biostudies-literature
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