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MetabolomicsPolymicrobial detection and metabolomics in saliva of children with early childhood caries

Cariogenic microorganisms as well as salivary metabolic status in early childhood caries (ECC) have been reported to differ from that in adult caries. The main aim of this study was to identify specific microbial species and salivary metabolites in children with ECC using species-specific qPCR an...

2024-11-12 | MTBLS10890 | MetaboLights
MetabolomicsProfiling the metabolome of uterine fluid for early detection of ovarian cancer

Ovarian cancer (OC) causes high mortality in women because of ineffective biomarkers for early diagnosis. Here, we perform metabolomics analysis on an initial training set of uterine fluid from 96 gynecological patients. A seven-metabolite-marker panel consisting of vanillylmandelic acid, norepin...

2023-03-06 | MTBLS4861 | MetaboLights
TranscriptomicsImproved detection of global copy number variation using high density, non-polymorphic oligonucleotide probes
Goal: To identify copy number variation in normal individuals using high density, non-polymorphic oligonucleotide probes Background DNA sequence diversity within the human genome may be more greatly affected by copy number variations (CNVs) than single nucleotide polymorphisms (SNPs). Although the ...
ORGANISM(S): Homo sapiens 
2008-04-24 | E-GEOD-9053 | biostudies-arrayexpress
TranscriptomicsActivity of the Bacillus anthracis 20 kDa protective antigen component
Edema factor of anthrax binds to the protective antigen (PA83) which cleaves to PA63 and PA20. The role of PA20 was examined using highthroughput gene expression analysis of human peripheral blood mononuclear cells (PBMC) exposed to PA20. Keywords: Toxicity determination PBMC obtained from differe...
ORGANISM(S): Homo sapiens 
2008-08-26 | E-GEOD-12533 | biostudies-arrayexpress
ProteomicsAntigen array profiling for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions
Antigen Arrays from Figures 2, 4, and 6 of Haab, Dunham, and Brown, Genome Biology 2001 2(2): research0004.1-0004.13
ORGANISM(S): Homo sapiens 
2005-06-30 | E-SMDB-103 | biostudies-arrayexpress
GenomicsNon-SARS-CoV-2 respiratory viral detection and whole genome sequencing from COVID-19 rapid antigen test devices
Respiratory virus detection from rapid antigen tests
PRJEB67729 | ENA
ProteomicsAntigen array profiling for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions (100X FCS)
Antigen Arrays with 100X FCS from Figure 7 of Haab, Dunham, and Brown, Genome Biology 2001 2(2): research0004.1-0004.13
ORGANISM(S): Homo sapiens 
2005-06-30 | E-SMDB-102 | biostudies-arrayexpress
TranscriptomicsCytokine-independent detection of antigen-specific germinal center T follicular helper (Tfh) cells in immunized non-human primates using a live cell Activation Induced Marker (AIM) technique
A range of current candidate AIDS vaccine regimens are focused on generating protective HIV neutralizing antibody responses. Many of these efforts rely on the rhesus macaque animal model. Understanding how protective antibody responses develop and how to increase their efficacy are both major knowle...
ORGANISM(S): Macaca mulatta 
2016-09-07 | E-GEOD-81382 | biostudies-arrayexpress
TranscriptomicsIdentification of Six Potential Markers for the Detection of Circulating Canine Mammary Tumor Cells in the Peripheral Blood
Circulating tumor cells in the peripheral have proven to be independent prognostic factors for overall survival the monitoring of therapeutic success of human breast cancer patients. Postmortem morphologic evidence also points towards the presence of circulating tumor cells in the peripheral blood o...
ORGANISM(S): Canis lupus familiaris 
2011-12-10 | E-GEOD-25586 | biostudies-arrayexpress
ProteomicsProfiling antibody function on antigen arrays
Humoral immune responses are traditionally characterized by determining the presence and quality of antibodies specific for certain antigens. Arraying of large numbers of antigens allows the parallel measurement of antibodies, generating patterns called antibody profiles. Functional characterization...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-12943 | biostudies-arrayexpress
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