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MetabolomicsMetabolomic mechanisms of antimicrobial peptides against Helicobacter pylori

Metabolomic mechanisms of antimicrobial peptides against Helicobacter pylori. By establishing treatment and control models combined with untargeted metabolomic analysis, this study aims to reveal the key metabolic pathway alterations and metabolic network reprogramming induced by antimicrobial pe...

2026-02-10 | MTBLS13884 | MetaboLights
MetabolomicsHypusination Orchestrates the Antimicrobial Response of Macrophages
Innate responses of myeloid cells defend against pathogenic bacteria via inducible effectors. Deoxyhypusine synthase (DHPS) catalyzes the transfer of the N-moiety of spermidine to the lysine-50 residue of eukaryotic translation initiation factor 5A (EIF5A) to form the amino acid hypusine. Hypusinate...
2021-04-06 | MTBLS607 | MetaboLights
MetabolomicsAntimicrobial Efficacy of Bifidobacterium longum FB1-4 Cell-Free Supernatant Against MRSA: Insights into Mechanisms and Food Matrix Application

The food safety landscape faces a significant challenge from methicillin-resistant Staphylococcus aureus (MRSA), a virulent and antibiotic-resistant foodborne pathogen. This study investigates the antimicrobial properties and mechanisms of cell-free supernatant (CFS) from Bifidobacterium longum F...

2026-02-26 | MTBLS13481 | MetaboLights
MetabolomicsApplication of the Protease-Resistant Antimicrobial Peptide R7I, Composed of Natural Amino Acids, as a Functional Food Ingredient for Modulating Intestinal Health

Foodborne pathogenic bacterial infections pose significant challenges to global food safety and public health, while the issue of antimicrobial resistance (AMR) has worsened in recent years, creating an urgent need for safe, natural alternatives to combat foodborne pathogens and associated intest...

2025-11-09 | MTBLS13292 | MetaboLights
MetabolomicsMetabolomic and Proteomic Profiling of the Antimicrobial Potentials from Lactobacillus johnsonii KD1 Cell-Free Supernatant against Foodborne Pathogenic Bacteria

This study characterized functions and metabolic profiles of cell-free supernatants (CFS) from Lactobacillus johnsonii KD1 against three foodborne pathogens: the Gram-negative bacteria Vibrio parahaemolyticus 3HP and Salmonella enterica serovar ...

2026-09-24 | MTBLS14550 | MetaboLights
MetabolomicsMolecular Omics Unveils the Antimicrobial Mechanism of UV-LED-Induced Chitosan Composite Film Against Penicillium itali-cum

Penicillium italicum (P. italicum) is a primary pathogen responsible for postharvest decay in citrus fruits, resulting in substantial economic losses. Chitosan and titanium dioxide and silver (CTS&TiO2&Ag) composite film solutions activated by combined UV and LED light represent innovativ...

2026-06-08 | MTBLS14711 | MetaboLights
MetabolomicsMutasynthetic production and antimicrobial characterisation of Darobactin darobactin analogs (NMR analysis)
Not available
ORGANISM(S): Escherichia coli 
ST001994 | MetabolomicsWorkbench
MetabolomicsMutasynthetic production and antimicrobial characterisation of Darobactin darobactin analogs (MS analysis)
Not available
ORGANISM(S): Escherichia coli 
ST001995 | MetabolomicsWorkbench
TranscriptomicsThe antimicrobial peptide-sensing system aps of Staphylococcus aureus
Staphylococcus aureus is a leading cause of hospital-associated infections. In addition, highly virulent strains of methicillin-resistant S. aureus (MRSA) are currently spreading outside health care settings. Survival in the human host is largely defined by the ability of S. aureus to resist mechani...
ORGANISM(S): Staphylococcus aureus 
2008-04-06 | E-GEOD-8400 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by tiling array of Antimicrobial Treatment Improves Mycobacterial Survival in Non-Permissive Growth Conditions.
Antimicrobials targeting cell wall biosynthesis are generally considered inactive against non-replicating bacteria. Paradoxically, we found that in non-permissive growth conditions exposure of Mycobacterium bovis BCG bacilli to such antimicrobials enhanced their survival. We identified a transcripti...
ORGANISM(S): Mycobacterium tuberculosis 
2014-02-28 | E-BUGS-123 | biostudies-arrayexpress
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