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ProteomicsANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes
Phase transitions of cellular proteins and lipids play a key role in governing the organisation and coordination of intracellular biology. Recent work has raised the intriguing prospect that phase transitions in proteins and lipids can be co-regulated. Here we investigate this possibility in the rib...
ORGANISM(S): Homo sapiens (Human) 
2025-02-19 | PXD060971 | Pride
Lc-msms Rnp granules Anxa11 
ProteomicsHeteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP Type C
Neurodegenerative diseases are characterised by the abnormal filamentous assembly of specific proteins in the central nervous system1. Human genetic studies established a causal role for protein assembly in neurodegeneration2. However, the underlying molecular mechanisms remain largely unknown, whic...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055345 | Pride
Frontotemporal dementia Neurodegenerative disease Tdp-43 and tmem106b 
UnknownSemantic variant primary progressive aphasia with ANXA11 p.D40G.
Not available
S-EPMC11881632 | biostudies-literature
UnknownCommon pathophysiology for ANXA11 disorders caused by aspartate 40 variants.
Not available
S-EPMC10014011 | biostudies-literature
UnknownAn ANXA11 P93S variant dysregulates TDP-43 and causes corticobasal syndrome.
Not available
S-EPMC11350008 | biostudies-literature
UnknownAn ANXA11 P93S variant dysregulates TDP-43 and causes corticobasal syndrome.
Not available
S-EPMC10602153 | biostudies-literature
UnknownAssociation of ANXA11 genetic variation with sarcoidosis in African Americans and European Americans.
Not available
S-EPMC3595044 | biostudies-literature
UnknownANXA11 mutations are associated with amyotrophic lateral sclerosis-frontotemporal dementia.
Not available
S-EPMC9549789 | biostudies-literature
UnknownPhysiological and pathological roles of ANXA11: a multifunctional regulator in neurodegeneration and other disorders.
Not available
S-EPMC12870404 | biostudies-literature
UnknownClinical and genetic characteristics of amyotrophic lateral sclerosis patients with ANXA11 variants.
Not available
S-EPMC9707645 | biostudies-literature
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