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TranscriptomicsAll-iPS cell mice generated from terminally differentiated B cells
The generation of induced pluripotent stem cells (iPSCs) often results in aberrant silencing of the imprinted Dlk1-Dio3 gene cluster, which compromises their ability to generate entirely iPSC-derived mice (“all-iPSC mice”). Here, we show that reprogramming in the presence of ascorbic acid attenu...
ORGANISM(S): Mus musculus 
2012-02-01 | E-GEOD-34761 | biostudies-arrayexpress
TranscriptomicsDefining a molecular roadmap of cellular reprogramming into iPS cells [miRNA profiling]
Factor induced reprogramming is a slow and inefficient process with only rare cells progressing towards induced pluripotent stem cells (iPSCs). Owing to these restraints, mechanistic studies have been limited to analyses of heterogeneous bulk populations undergoing reprogramming and partially reprog...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-42475 | biostudies-arrayexpress
GenomicsDefining a molecular roadmap of cellular reprogramming into iPS cells [ChIP-Seq]
Factor induced reprogramming is a slow and inefficient process with only rare cells progressing towards induced pluripotent stem cells (iPSCs). Owing to these restraints, mechanistic studies have been limited to analyses of heterogeneous bulk populations undergoing reprogramming and partially reprog...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-42477 | biostudies-arrayexpress
TranscriptomicsDefining a molecular roadmap of cellular reprogramming into iPS cells [mRNA profiling]
Factor induced reprogramming is a slow and inefficient process with only rare cells progressing towards induced pluripotent stem cells (iPSCs). Owing to these restraints, mechanistic studies have been limited to analyses of heterogeneous bulk populations undergoing reprogramming and partially reprog...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-42379 | biostudies-arrayexpress
TranscriptomicsEarly passage mouse induced pluripotent stem (iPS) cells derivated from various somatic cell origins
Induced pluripotent stem (iPS) cells have been derived from various somatic cell populations through ectopic expression of defined factors. It remains unclear whether iPS cells generated from different cell types are molecularly and functionally similar. Here, we show that iPS cells obtained from fi...
ORGANISM(S): Mus musculus 
2010-07-19 | E-GEOD-22908 | biostudies-arrayexpress
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