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Triggering ferroptosis has recently been demonstrated to be a promising approach for cancer treatment. However, the application of current ferroptosis inducers, such as GPX4 inhibitors, was rather limited due to their pharmaceutical or safety issues, which evoking the discovery of new favorable cand...
ORGANISM(S): Homo sapiens 
2025-12-09 | GSE284669 | GEO
Objective: To examine the effects of the phytoestrogen metabolite, equol, on gene expression in the monkey iliac artery. Design: Eight ovariectomized cynomolgus monkeys were on a high fat diet for 6.5 years. The left iliac artery was biopsied prior to randomization to equol (0.0237 g/100 g chow, ...
ORGANISM(S): Macaca fascicularis 
Therapeutic Perturbation of Liver and Bile Duct Cancer through Targeted Inhibition of FSP1 and GCS Induced Ferroptosis
Goal of the experiment: To examine differential gene expression in the iliac arteries of cynomolgous monkeys in the presence of small, medium, or large atherosclerotic plaque. Brief description of the experiment: Objective: To examine global gene expression patterns in the iliac arteries of mon...
ORGANISM(S): Macaca fascicularis 
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