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TranscriptomicsA mutation of RNA polymerase β’ subunit (RpoC) converts heterogeneously vancomycin-intermediate S. aureus (hVISA) into ‘slow-VISA’ (sVISA)
Various mutations in the rpoB gene, which encodes the RNA polymerase beta subunit, are associated with increased vancomycin (VAN) resistance in vancomycin-intermediate S. aureus (VISA) and hetero-VISA (hVISA) strains. We reported that rpoB mutations are also linked to the expression of the recently ...
ORGANISM(S): Staphylococcus aureus 
2015-05-08 | E-GEOD-65338 | biostudies-arrayexpress
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Cell NAMPTi treatment)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7251 | MetaboLights
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAD targeted time-course)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7253 | MetaboLights
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAMPT targeted therapy)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7252 | MetaboLights
UnknownAssociation of cancer progression with elevated expression of programmed cell death protein 1 ligand 1 by upper tract urothelial carcinoma and increased tumor-infiltrating lymphocyte density.
Not available
S-EPMC7183489 | biostudies-literature
UnknownMethylation pattern of urinary DNA as a marker of kidney function decline in diabetes.
Not available
S-EPMC7473659 | biostudies-literature
UnknownComparison of survival times of advanced cancer patients with palliative care at home and in hospital.
Not available
S-EPMC10101528 | biostudies-literature
UnknownDeciphering state-dependent immune features from multi-layer omics data at single-cell resolution.
Not available
S-EPMC12339405 | biostudies-literature
UnknownPancreatic glycoprotein 2 is a first line of defense for mucosal protection in intestinal inflammation.
Not available
S-EPMC7887276 | biostudies-literature
UnknownGermline variants and mosaic chromosomal alterations affect COVID-19 vaccine immunogenicity.
Not available
S-EPMC11960526 | biostudies-literature
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