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UnknownImpact of a planned dose interruption of dacomitinib in the treatment of advanced non-small-cell lung cancer (ARCHER 1042).
Not available
S-EPMC5552055 | biostudies-literature
TranscriptomicsRMA expression data for liver samples from subjects with HCV cirrhosis with and without concomitant HCC
In this study, we used the Affymetrix HG-U133A 2.0 GeneChip for deriving a multigenic classifier capable of predicting HCV+cirrhosis with vs without concomitant HCC. We studied gene expression in cirrhotic tissues with (N=16) and without (N=47) HCC. Keywords: cross-sectional Liver tissue samples we...
ORGANISM(S): Homo sapiens 
2009-09-11 | E-GEOD-17967 | biostudies-arrayexpress
UnknownA phase II study (ARCHER 1042) to evaluate prophylactic treatment of dacomitinib-induced dermatologic and gastrointestinal adverse events in advanced non-small-cell lung cancer.
Not available
S-EPMC6279098 | biostudies-literature
TranscriptomicsDifferential gene expression analysis of MAT1-1 and MAT1-2 strains in Aspergillus oryzae
The potential for sexual reproduction in Aspergillus oryzae was assessed by investigating the presence and functionality of MAT genes. Previous genome studies had identified a MAT1-1 gene in the RIB40 reference strain. We now report the existence of a complimentary MAT1-2 gene and sequencing of an i...
ORGANISM(S): Aspergillus oryzae 
2012-04-29 | E-GEOD-33542 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression analysis upon constitutive activation of the HacA bZIP transcription factor in Aspergillus niger
Background: HacA/Xbp1 is a conserved bZIP transcription factor in eukaryotic cells which regulates gene expression in response to various forms of secretion stress and as part of secretory cell differentiation. In the present study, we replaced the endogenous hacA gene of an Aspergillus niger strain...
ORGANISM(S): Aspergillus niger 
2012-08-06 | E-GEOD-39070 | biostudies-arrayexpress
TranscriptomicsOutcomes of Allogeneic Hematopoietic Cell Transplantation in Adults with fusions associated with Ph-like ALL
Allogenic hematopoietic cell transplantation (alloHCT) is a well-established curative modality for adults with high-risk ALL; yet large data describing alloHCT outcomes in Philadelphia (Ph)-like ALL is lacking. We retrospectively analyzed archived DNA samples from consecutive adults with B-cell Ph-n...
ORGANISM(S): Homo sapiens 
2022-08-01 | E-MTAB-11954 | biostudies-arrayexpress
TranscriptomicsGenome-wide Transcriptional Responses of the Filamentous Fungus Aspergillus niger to Lignocellulose (Wheat straw) using RNA-sequencing
We have studied the physiological response of the fungus Aspergillus niger when exposed to wheat straw as a model lignocellulosic substrate. Using RNA-sequencing we showed that, 24 hours after exposure to straw, gene expression of known plant cell wall degrading enzymes represents a huge investment ...
ORGANISM(S): Aspergillus niger 
2012-08-27 | E-GEOD-33852 | biostudies-arrayexpress
UnknownExcess of guide RNA reduces knockin efficiency and drastically increases on-target large deletions.
Not available
S-EPMC10074149 | biostudies-literature
TranscriptomicsThe role of carbon starvation in the induction of enzymes that degrade plant-derived carbohydrates in Aspergillus niger
Fungi are an important source of enzymes for saccharification of plant polysaccharides and production of biofuels. Understanding of the regulation and induction of expression of genes encoding these enzymes is still incomplete. To explore the induction mechanism, we analysed the response of the indu...
ORGANISM(S): Aspergillus niger 
2014-08-22 | E-GEOD-57315 | biostudies-arrayexpress
UnknownDevelopment of a Staphylococcus aureus reporter strain with click beetle red luciferase for enhanced in vivo imaging of experimental bacteremia and mixed infections.
Not available
S-EPMC6853927 | biostudies-literature
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